Protein Alignment swm and rbm26

DIOPT Version :10

• Sequence 1: NP_001260586.1
• Gene: swm / 35235
• FlyBaseID: FBgn0002044
• Length: 1063
• Species: Drosophila melanogaster
• Sequence 2: NP_998868.1
• Gene: rbm26 / 407926
• XenbaseID: XB-GENE-960053
• Length: 626
• Species: Xenopus tropicalis
• Alignment Length: 788
• Identity: 196/788 - (24%)
• Similarity: 300/788 - (38%)
• Gaps: 280/788 - (35%)

  Fly     1 MILENSDKLKDWLSVVLEPLCDADSSALARYVIALLKKDKSDKDLKRIMIEQLDVFLSEETTRFV 65
            ||:|:.:.||.|||..|||:||||.||||:||:||:||||:|::||.:.|:||||||.:||..||
 Frog     1 MIIEDFEALKHWLSKTLEPICDADPSALAKYVLALVKKDKTDRELKALCIDQLDVFLQKETQGFV 65

  Fly    66 ERLFDAIASEEYLTVPAAPLITASSASTAELTVDQELALVIDGPQDDIEAVLVADSPPPPPKDNV 130
            ::|||||.::.||..|       .|.|||.:.:|     ..:..:.:|:            ||.|
 Frog    66 DKLFDAINTKNYLPQP-------DSTSTAVVKLD-----TFEHQEREIK------------KDEV 106

  Fly   131 IKPDSNQVK----LEQASQDAREAEALAFISQEAGIAMHVPTDAKPAFDQHK-----TKDSHNQQ 186
            .|.:..:.|    |.|:.|                          |:..:||     .|.|::.:
 Frog   107 NKEEEKEKKAPRRLNQSPQ--------------------------PSITRHKETRENRKRSNSDR 145

  Fly   187 SASNYQHHHVRSASP---------PGRSSGVSGSGGGGPGGAGLAAGYADKENQPRDSRRRRASL 242
            .:|:.| :..||..|         |.|.|......         |.....::::.|:.|.|:...
 Frog   146 ESSSIQ-NSFRSGLPEQKLDVDAAPTRLSSNKVQN---------AKNIRSRDDRKREDRFRKREY 200

  Fly   243 -----------------RSRSRSRSRSNERAFRRSRSRDRRVNEREKTQRQFRNKSPPGSQTDNR 290
                             |.||||.|||..|::.:.|.|||   ||::::.:.|::        ::
 Frog   201 DRNVPRRDLYRDRYNRRRGRSRSYSRSRSRSWSKERQRDR---ERDRSRSRTRSR--------DK 254

  Fly   291 HHGRRNFDRRRIGGNADDRPRFGNNKSRRSHSRSMSPERNARRNQNSPDRVQTAQANLIPAP--- 352
            ..|:..||..|                       ..|..|:..:.:|...:..|.   .|.|
 Frog   255 DSGKPKFDLDR-----------------------SDPVDNSYASGSSVSHIGPAH---FPVPTLS 293

  Fly   353 --VAPPAPVEH--------PASH--------------PRQRCRDFDEKGYCVRGETCPWDHGVNP 393
              :....|..|        |..|              |::||||:||||:|:||:.||:|||.:|
 Frog   294 STITVITPSHHGNSSAENWPEFHEDQVDHSNYGRPQIPKKRCRDYDEKGFCMRGDMCPFDHGSDP 358

  Fly   394 VVFEGINNTSLMMSMREYNPDAPEIWARSGGPPPGAGQGPVPPPTQPGQTTINPFSGNVRPTTLM 458
            ||.|.:|...::....:  |.|.|     |.||||.   |.|||      .:.|...|:||
 Frog   359 VVVEDVNLPGILPFPAQ--PPAVE-----GPPPPGL---PPPPP------LLTPPPVNLRP---- 403

  Fly   459 SGSGPSPMGVPNPADYARNPGAPP------QAAMMPFPFNPTAVTTPLQRQLIPI---------- 507
                  |:..|.|..    |..||      |..:.......|......|..|.|:
 Frog   404 ------PVPPPGPLP----PSLPPITENEVQVRLRTIREQVTESQMWDQNSLFPVKRRKQVYVNR 458

  Fly   508 ----PVVDGAPTGGVAEVG--KRRFELEDTVAIADVPTKRKVPINSRLGPRVNPNMQQHNSSLEL 566
                .:::...|..:.:.|  :|.::|         |...|:.:|..         ...:|.|:.
 Frog   459 CFLKKIMEPGKTSDIEKNGMLERCYQL---------PRTEKLQVNKG---------TSDSSQLQF 505

  Fly   567 RKVPRGLNTIAHLNNHFAKFGKIVNIQVSYEGDPEAAI----------VTFSTHAEANVAYRSTE 621
            ..    ||.:....:.|      |..|.|.|.|.|...          |......|.::
 Frog   506 NM----LNKMQGYQDAF------VQPQYSKELDEETGFCKTLIPYMRRVPLDRRLEMHI------ 554

  Fly   622 AVLNNRFIKVFWHNDSSGADVGQMNQMGGGGGGGGRKNASQYHLHNVPA-VPTP---NADGAKIS 682
            ||||  .|..|..:.:|                .|:..:..:   .:|: :|||   ||..:.||
 Frog   555 AVLN--CISSFCQSPAS----------------SGQNPSVPF---TIPSLLPTPLSVNASRSCIS 598

  Fly   683 NANPLTEA 690
            :..|.:::
 Frog   599 DIPPYSQS 606

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
swm	NP_001260586.1	RRM1_RBM26_like	561..634	CDD:409702	19/82 (23%)
		RRM2_RBM26_like	921..992	CDD:409703
rbm26	NP_998868.1	PWI	7..72	CDD:460224	41/64 (64%)
		ZnF_C3H1	<335..355	CDD:214632	13/19 (68%)