Protein Alignment Ctu2 and CTU2

DIOPT Version :10

• Sequence 1: NP_609975.1
• Gene: Ctu2 / 35234
• FlyBaseID: FBgn0032793
• Length: 405
• Species: Drosophila melanogaster
• Sequence 2: NP_001305436.1
• Gene: CTU2 / 348180
• HGNCID: 28005
• Length: 586
• Species: Homo sapiens
• Alignment Length: 580
• Identity: 138/580 - (23%)
• Similarity: 209/580 - (36%)
• Gaps: 213/580 - (36%)

  Fly     1 MCSIGEDDFGDEGAAHAMVVESLPLGIVLSPGNCSKCD-------VNSGELYKLNFRTAECRECF 58
            ||.:|| |:|:....     |..|.........|.||.       :.:|:.:        ||:||
Human     1 MCQVGE-DYGEPAPE-----EPPPAPRPSREQKCVKCKEAQPVVVIRAGDAF--------CRDCF 51

  Fly    59 LAYARHKFRAALGAAKILPRNAEVLLVLDGSAESLVLLDMLHFAQTQNTFKRLHCNARVVYVEEQ 123
            .|:..|||||.||..:::....:|||...|...|..::..:....:|::.|||...|.|::|:|
Human    52 KAFYVHKFRAMLGKNRLIFPGEKVLLAWSGGPSSSSMVWQVLEGLSQDSAKRLRFVAGVIFVDE- 115

  Fly   124 QVQGRDPVDLEALQRLSTQYAPF-----------------------DFYVIELG---ALP-SSL- 160
                |.|..|....|.:.:..|.                       .|..:|:.   ||| |||
Human   116 ----RTPGVLTVALRSAAREKPLPKGKWPTPHSSARKHRPAERGLEGFSQVEVALQPALPGSSLS 176

  Fly   161 ----------------------QRIKDYSPFLNAN------------------------NELI-- 177
                                  :.:.:..|.|.|.                        .||:
Human   177 PDSFCLGFSEGAACGQSLEERSKTLAEVKPILQATGFPWHVVALEEVFSLPPSVLWCSAQELVGS 241

  Fly   178 ---------------HKL----------------------QKL-------------------RSL 186
                           |.|                      |.|                   |:|
Human   242 EGAYKAAVDSFLQQQHVLGAGGGPGPTQGEEQPPQPPLDPQNLARPPAPAQTEALSQLFCSVRTL 306

  Fly   187 TARQDYLQQQRKNLICSVAQCLQCTHVFESNISVDLATQLLTAIALGRGGSAALDVALLDDRLSG 251
            ||:::.||..|.:||..:|:....:.|...:....||.:|:|.:|||||...|.|....|:| .|
Human   307 TAKEELLQTLRTHLILHMARAHGYSKVMTGDSCTRLAIKLMTNLALGRGAFLAWDTGFSDER-HG 370

  Fly   252 DVKLLRPLKDLTEQEIQFYIHAQRLKPHFQKGSRY----GMEHGETASLQNLTSAFVANLQQNFA 312
            ||.::||::|.|.:|:.||   .||   |...|.:    ..:..|.||:..|..||:..||..|.
Human   371 DVVVVRPMRDHTLKEVAFY---NRL---FSVPSVFTPAVDTKAPEKASIHRLMEAFILRLQTQFP 429

  Fly   313 STVSTVFRTGDKI---------AVNSNPEQSSCVHCRSTLDSELSD--TLLAIEYSRSVSE---- 362
            ||||||:||.:|:         |.:|.|.   |:.|...||.:.:|  |....:.|..:|:
Human   430 STVSTVYRTSEKLVKGPRDGPAAGDSGPR---CLLCMCALDVDAADSATAFGAQTSSRLSQMQSP 491

  Fly   363 ---------------AGVS-LYKSGQDLEGLAKKR-----LENKDGLCHACRAIQTELDS 401
                           .||. ..:.||   |..::.     :|.:  ||::||....:|.|
Human   492 IPLTETRTPPGPCCSPGVGWAQRCGQ---GACRREDPQACIEEQ--LCYSCRVNMKDLPS 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ctu2	NP_609975.1	CTU2	295..393	CDD:463044	35/133 (26%)
CTU2	NP_001305436.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..24		8/28 (29%)
		TilS	<315..442	CDD:439807	49/133 (37%)
		CTU2	412..539	CDD:463044	36/134 (27%)