DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18094 and Nudt1

DIOPT Version :9

Sequence 1:	NP_001260584.1	Gene:	CG18094 / 35232	FlyBaseID:	FBgn0032791	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	NP_001343512.1	Gene:	Nudt1 / 17766	MGIID:	109280	Length:	156	Species:	Mus musculus

Alignment Length:	116	Identity:	25/116 - (21%)
Similarity:	39/116 - (33%)	Gaps:	26/116 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 ALRETFEEVGILICTEQDDIQKWDSKSGHPRTVLLESSE----HFEWQHRVHNDASQFLELFRHY 168
            |.||..||.|:.:.|..        |.||.....:.|.|    |......||...::..|:...:
Mouse    49 AKRELLEESGLSVDTLH--------KVGHISFEFVGSPELMDVHIFSADHVHGTPTESEEMRPQW 105

  Fly   169 KVIPNIWSLQEW---SIWRTAATANRKY---------DTV--YYITMLDKY 205
            ..:..|.....|   |.|.......:|:         ||:  |.:..:|.:
Mouse   106 FQLDQIPFADLWPDDSYWFPLLLQKKKFCGHFKFQDQDTILSYSLREVDSF 156

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18094	NP_001260584.1	None
Nudt1	NP_001343512.1	MTH1	6..140	CDD:239519	21/98 (21%)
		Substrate binding. /evidence=ECO:0000269\|PubMed:29281266, ECO:0007744\|PDB:5MZE	35..38
		Nudix box. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00794	37..58		5/8 (63%)
		Substrate binding. /evidence=ECO:0000269\|PubMed:29281266, ECO:0007744\|PDB:5MZE	117..120		1/2 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0494
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900