DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG18094 and DCP2

DIOPT Version :10

Sequence 1:NP_609974.3 Gene:CG18094 / 35232 FlyBaseID:FBgn0032791 Length:360 Species:Drosophila melanogaster
Sequence 2:NP_689837.2 Gene:DCP2 / 167227 HGNCID:24452 Length:420 Species:Homo sapiens


Alignment Length:185 Identity:42/185 - (22%)
Similarity:70/185 - (37%) Gaps:65/185 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly    44 NHCVF--PGGVFDPIEDQSAKWITF---FKSFG--VTDEQLK--------MCRHNQDSPRPEFLS 93
            :||.|  |.|  :.:|....:|..:   ..::|  :.||.|:        :.:.....|:.:   
Human    71 SHCPFLLPQG--EDVEKVLDEWKEYKMGVPTYGAIILDETLENVLLVQGYLAKSGWGFPKGK--- 130

  Fly    94 GGDHISRDIALRLTALRETFEEVGI----LICTEQDD------------------IQKWDSKSGH 136
                ::::.|....|.||.|||.|.    .||  :||                  |.| |:|. :
Human   131 ----VNKEEAPHDCAAREVFEETGFDIKDYIC--KDDYIELRINDQLARLYIIPGIPK-DTKF-N 187

  Fly   137 PRTVLLESSEHFEW-------QHRVHNDASQFLEL----FRHYKVIPNIWSLQEW 180
            |:|  .....:.||       .||  ||.:...:|    .:.:..||.|..|::|
Human   188 PKT--RREIRNIEWFSIEKLPCHR--NDMTPKSKLGLAPNKFFMAIPFIRPLRDW 238

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG18094NP_609974.3 NUDIX_Hydrolase 10..251 CDD:469772 42/185 (23%)
DCP2NP_689837.2 DCP2 12..93 CDD:428265 7/23 (30%)
NUDIX_Dcp2p_Nudt20 97..246 CDD:467540 35/157 (22%)
Nudix box 129..150 7/27 (26%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 246..266
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 313..344
Blue background indicates that the domain is not in the aligned region.

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