DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10194 and Nudt19

DIOPT Version :9

Sequence 1:	NP_609973.1	Gene:	CG10194 / 35231	FlyBaseID:	FBgn0032790	Length:	351	Species:	Drosophila melanogaster
Sequence 2:	NP_001004258.1	Gene:	Nudt19 / 308518	RGDID:	1302935	Length:	357	Species:	Rattus norvegicus

Alignment Length:	313	Identity:	115/313 - (36%)
Similarity:	161/313 - (51%)	Gaps:	26/313 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 SSLILLAKNQVEKSTSCDYNALLLTRTQKSTFMPESSVFPGGVCDASDSSPAWLEHFQRNEFSAA 76
            ::.::||......|.: .:..|||.|.|...|||.:.||||||.||:||||.|:..|...
  Rat    10 AATVMLAAGWSHASPA-GFRLLLLQRAQNQRFMPGAHVFPGGVLDAADSSPDWVSLFAPR----- 68

  Fly    77 KLRNVGHVK-----GPR-------PDIFHTKADKKSLDPSLALRLTAIRETFEELGILLCRDSKS 129
                  |..     ||.       |.:||..||..:|...:|||:.||||||||.|:||.|...|
  Rat    69 ------HTPPRFGLGPEPPRQPSFPGLFHGDADGAALPDDVALRICAIRETFEEAGVLLLRPRDS 127

  Fly   130 LTSTSDYG-AFYDQFDRAHWQHIVHNNASQFLELCKQLDVLPDVWSLHEWSVWRTP-STFKKRFE 192
            ..::.:.. |.......|.|:..|.::...||:||..||..||:|:||:|..|.|| ....:||:
  Rat   128 ARASQEPSIALSPPAGLADWRSRVRSDPRCFLQLCAHLDCTPDIWALHDWGGWLTPYGRSSRRFD 192

  Fly   193 TAFFMTALEQEPRVHIEPNEVKDSAWRSPLDYLQASLRKELWLPPPQFYELSRCLNFSSLDNLRQ 257
            |.|.:..|.:.|||..:..||....|.||.:..:..|.||:||.||||||:.|..||:||..|.:
  Rat   193 TTFLLCCLRETPRVEPDLAEVVGYKWLSPSEATECFLSKEIWLAPPQFYEVRRLENFASLSALYR 257

  Fly   258 FAAEREVKGIQLIHPVVHKCTNGLVHLLPGDDAYPADPDASNEKIEIDLSVEE 310
            |..:..::..:...|:|...::|.:||||||:.|....|...:.:.||...||
  Rat   258 FCLDHPLEVPEKWLPIVLLTSDGSIHLLPGDELYVKGSDFLEKNMSIDKKTEE 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	Identity
CG10194	NP_609973.1	None
Nudt19	NP_001004258.1	Nudix box	97..118	12/20 (60%)
Nudt19	NP_001004258.1	Microbody targeting signal. /evidence=ECO:0000255	355..357
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351948
Domainoid	1	1.000	194	1.000	Domainoid score	I3070
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H13211
Inparanoid	1	1.050	195	1.000	Inparanoid score	I3750
OMA	1	1.010	-	-		QHG48383
OrthoDB	1	1.010	-	-		D1417901at2759
OrthoFinder	1	1.000	-	-		FOG0004004
OrthoInspector	1	1.000	-	-		otm44910
orthoMCL	1	0.900	-	-		OOG6_103951
Panther	1	1.100	-	-	LDO	PTHR12318
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2766
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.910