DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10194 and DCP2

DIOPT Version :9

Sequence 1:	NP_609973.1	Gene:	CG10194 / 35231	FlyBaseID:	FBgn0032790	Length:	351	Species:	Drosophila melanogaster
Sequence 2:	NP_689837.2	Gene:	DCP2 / 167227	HGNCID:	24452	Length:	420	Species:	Homo sapiens

Alignment Length:	162	Identity:	32/162 - (19%)
Similarity:	53/162 - (32%)	Gaps:	45/162 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 AKNQVEKSTSCDYNALLLTRTQKSTFMPESSVFPGGVCDASDSSPA--WLEHFQ-------RNEF 73
            ||..|||          |:||:   |.....:||       |.||.  |::|.|       .|..
Human   261 AKPTVEK----------LSRTK---FRHSQQLFP-------DGSPGDQWVKHRQPLQQKPYNNHS 305

  Fly    74 SAAKLRNVGHVKGPRPDIFHTKADKKSLDPSLALRLTAIRETFEELGILLCRDS---KSLTSTSD 135
            ..:.|     :||....:......:....|:...|...::...::..::.|...   :.|....:
Human   306 EMSDL-----LKGKNQSMRGNGRKQYQDSPNQKKRTNGLQPAKQQNSLMKCEKKLHPRKLQDNFE 365

  Fly   136 YGAFYD--------QFDRAHWQHIVHNNASQF 159
            ..|.||        ..:.|..|.:..|...:|
Human   366 TDAVYDLPSSSEDQLLEHAEGQPVACNGHCKF 397

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10194	NP_609973.1	None
DCP2	NP_689837.2	DCP2	12..93	CDD:309943
		Dcp2p	97..246	CDD:239644
		Nudix box	129..150
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	246..266		2/4 (50%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	313..344		3/30 (10%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0494
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900