DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10195 and NUDT14

DIOPT Version :9

Sequence 1:	NP_001260583.1	Gene:	CG10195 / 35228	FlyBaseID:	FBgn0032787	Length:	361	Species:	Drosophila melanogaster
Sequence 2:	NP_803877.2	Gene:	NUDT14 / 256281	HGNCID:	20141	Length:	222	Species:	Homo sapiens

Alignment Length:	194	Identity:	45/194 - (23%)
Similarity:	70/194 - (36%)	Gaps:	62/194 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 RRLVLIREDRPAILAPQGTGCYDRFFKRS-----RIWAREITLRL-----TAVRECFEEVGLLLC 133
            |.|||:::.|||:.|    |..:|.|..|     :...||:...|     ..|..|   .||:
Human    53 RSLVLVKQFRPAVYA----GEVERRFPGSLAAVDQDGPRELQPALPGSAGVTVELC---AGLV-- 108

  Fly   134 RSRSQLDFGAVTCAQAVPDLESWQR-RVHNKPAEFLTLCRELNVVPDLWALHEWSAWASPGFIRK 197
             .:..|....|.|.      |:|:. ..|..|::...:.               :.|:..| :..
Human   109 -DQPGLSLEEVACK------EAWEECGYHLAPSDLRRVA---------------TYWSGVG-LTG 150

  Fly   198 GHETVFFMAFVDKQPE-----LLEEPSEVKETLWLTPVE-LLRLAD-----------LGNVWFM 244
            ..:|:|:....|.|..     |:|| .|:.|.:.| |:| ....||           .|..||:
Human   151 SRQTMFYTEVTDAQRSGPGGGLVEE-GELIEVVHL-PLEGAQAFADDPDIPKTLGVIFGVSWFL 212

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10195	NP_001260583.1	NUDIX	10..237	CDD:278710	40/174 (23%)
NUDT14	NP_803877.2	TIGR00052	23..212	CDD:129162	44/192 (23%)
NUDT14	NP_803877.2	Nudix box	111..129		5/23 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0494
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900