DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10195 and Nudt19

DIOPT Version :9

Sequence 1:	NP_001260583.1	Gene:	CG10195 / 35228	FlyBaseID:	FBgn0032787	Length:	361	Species:	Drosophila melanogaster
Sequence 2:	NP_149071.2	Gene:	Nudt19 / 110959	MGIID:	94203	Length:	357	Species:	Mus musculus

Alignment Length:	364	Identity:	103/364 - (28%)
Similarity:	159/364 - (43%)	Gaps:	32/364 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 ASPTKWRTSASVILVSR-DDGNNKDYKVLMLKRSDATAIALNQTVFPGGLLDSGADESVAWL--- 65
            :|.:.||.:|:|:|.:. ...:...:::|:|:|:..........|||||:||: ||.|..|:
Mouse     2 SSSSSWRRAATVMLAAGWTHSSPAGFRLLLLQRAQNQRFLPGAHVFPGGVLDA-ADSSPDWVRLF 65

  Fly    66 ---HYLEEFGVPQEALRRLV---LIREDRPAILAPQGTGCYDRFFKRSRIWAREITLRLTAVREC 124
               |....||:..|..|:..   |...|......|.                 ::.||:.|:||.
Mouse    66 APRHTPPRFGLGPEPPRQPPFPGLSHGDADPAALPD-----------------DVALRICAIREA 113

  Fly   125 FEEVGLLLCRSRSQLDFGAVTCAQAVP--DLESWQRRVHNKPAEFLTLCRELNVVPDLWALHEWS 187
            |||.|:||.|.|..............|  .|..|:.||.:.|..||.||..|:..||:||||:|.
Mouse   114 FEEAGVLLLRPRDAAPASQEPSQALSPPAGLAEWRSRVRSDPRCFLQLCAHLDCTPDIWALHDWG 178

  Fly   188 AWASP-GFIRKGHETVFFMAFVDKQPELLEEPSEVKETLWLTPVELLRLADLGNVWFMPPQVYEL 251
            .|.:| |...:..:|.||:..:...|.:..:.:||....||:|.|.........:|..|||.||:
Mouse   179 GWLTPYGRTIRRFDTTFFLCCLRDIPRVEPDVAEVVGYQWLSPSEATECFLSKEIWLAPPQFYEM 243

  Fly   252 SRLMGIKAYQSLLEFAIKRSGLGTTMFLPIGYNCQGSMVFVLPGDDFYVPEPHLVHEIISFPGSE 316
            .||....:..:|..|...|.......:|||........:.:||||:.||.:...:.:.:|.....
Mouse   244 RRLENFASLSALYRFCSDRPSEVPEKWLPIILLTSDGTIHLLPGDELYVKDSDFLEKNMSTDKKT 308

  Fly   317 EEFRARSKHLHRYT-YGPGVRNLELNIAPPNGHLKPLKF 354
            ||.....|.|:|.. :.|.|..:.:.:...|.|:.|..:
Mouse   309 EEIVKEGKVLNRVVIHSPYVYEIYMTLPSENKHVYPRNY 347

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10195	NP_001260583.1	NUDIX	10..237	CDD:278710	71/239 (30%)
Nudt19	NP_149071.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	72..93		5/20 (25%)
		Nudix box	97..118		9/37 (24%)
		Microbody targeting signal. /evidence=ECO:0000255	355..357
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167848336
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0494
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48383
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004004
OrthoInspector	1	1.000	-	-		otm42845
orthoMCL	1	0.900	-	-		OOG6_103951
Panther	1	1.100	-	-	O	PTHR12318
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2766
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.710