DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tj and maf

DIOPT Version :9

Sequence 1:	NP_001260582.1	Gene:	tj / 35227	FlyBaseID:	FBgn0000964	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	NP_001027476.1	Gene:	maf / 613051	XenbaseID:	XB-GENE-6053271	Length:	346	Species:	Xenopus tropicalis

Alignment Length:	392	Identity:	117/392 - (29%)
Similarity:	166/392 - (42%)	Gaps:	104/392 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   147 VPSTPPETPPVVGS-----PTGS-SSCPAQTYAHHYARTPGSSVSVSASAAAAAAASAGAASVSA 205
            |...|.||..::..     ..|| ||.|..        ||.|||..|.|   .:|.|.|:.|...
Frog    32 VKKEPVETDRIISQCGRLIAGGSLSSTPMS--------TPCSSVPPSPS---FSAPSPGSGSEQK 85

  Fly   206 GLSHDMMWLTNSIRADQQPLDLRPLPYPGSQEEA---------EEWDRQRDYALQAAAAHHHHHG 261
            ....|..|::      ..|..:.|.....|.|:|         ::..:|:...|||.     :.|
Frog    86 SHLEDYYWMS------AYPQQINPEALGFSPEDAVEALISNSNQQQQQQQQQQLQAG-----YDG 139

  Fly   262 QPLMQAQHHPHGHGGHPHQ------------VMLQQSKYPHHHHHHFHNLELTPINMHSNSYGSA 314
              ..:.|.:. ..||.|.:            :....::.|||||||           |.:|.|..
Frog   140 --FARGQQYA-SSGGMPGEDMGSAAAVVSAVIAAAAAQNPHHHHHH-----------HHHSVGHQ 190

  Fly   315 SGALTPTCLPQVPSNGSGSSGGGGGSGSGSGGPGSVGGGSCVITRAALQPCRPLSASSTRSSNNM 379
            :|...|          .|.:||||.|||.:.  .||.|        ||.|  |.:.....
Frog   191 AGVQPP----------GGGTGGGGSSGSSTS--SSVVG--------ALHP--PAAHHHHH----- 228

  Fly   380 SPRTCSGAYSNATLEDCLNDDMLTTLTVRELNKRLHGCPREEVVRLKQKRRTLKNRGYAQNCRSK 444
                    :.:...:|..:|:.|.|::|||||::|.|..:|||:||||||||||||||||:||.|
Frog   229 --------HHHLHFDDRFSDEQLVTMSVRELNRQLRGVSKEEVIRLKQKRRTLKNRGYAQSCRFK 285

  Fly   445 RLHQRHELEKANRVLNQDLHRLKLEYSRVCQERDALMQRLQRAANGGVGAGGATAGGDSQSSPEF 509
            |:.|||.||.....|.|.:..||.|.||:.:||||..::.::....|....|      |.:|.::
Frog   286 RVQQRHVLESEKNQLLQQVEHLKQEISRLLRERDAYKEKYEKLLGSGFRENG------SSNSDKY 344

  Fly   510 YL 511
            ::
Frog   345 FM 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tj	NP_001260582.1	bZIP_Maf	397..486	CDD:281170	49/88 (56%)
tj	NP_001260582.1	coiled coil	419..486	CDD:269866	39/66 (59%)
maf	NP_001027476.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	57..85		13/38 (34%)
		Maf_N	87..119	CDD:285569	7/37 (19%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	173..234		27/106 (25%)
		bZIP_Maf_large	260..328	CDD:269866	39/67 (58%)
		coiled coil	260..328	CDD:269866	39/67 (58%)
		Basic motif. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00978	265..290		20/24 (83%)
		Leucine-zipper. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00978	293..314		8/20 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	103	1.000	Domainoid score	I6694
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	153	1.000	Inparanoid score	I4228
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1395389at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10129
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5055
SonicParanoid	1	1.000	-	-		X543
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.100