Protein Alignment tj and NRL

DIOPT Version :10

• Sequence 1: NP_001260582.1
• Gene: tj / 35227
• FlyBaseID: FBgn0000964
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: XP_011535103.2
• Gene: NRL / 4901
• HGNCID: 8002
• Length: 339
• Species: Homo sapiens
• Alignment Length: 331
• Identity: 96/331 - (29%)
• Similarity: 131/331 - (39%)
• Gaps: 70/331 - (21%)

  Fly   233 PGSQEEAEE---------------WDRQRDYALQA--------------AAAHHHHHGQP----- 263
            |||.|.:||               .:|.|:..:||              .|....|..:|
Human     4 PGSAERSEEREEVLRVADRDRAVRGERGREGEVQAETRSTGRLPSQETRGAGGWTHSSRPCPPPP 68

  Fly   264 ----LMQAQHH------PHG------HGGHPHQVM-LQQSKYPHHHHHHFHNLELTPINMHSNSY 311
                |.:|:..      |.|      |...|...| |..|.....:.:.|..::.......|...
Human    69 RMGNLAEAESRRAPLAAPRGRAQRKVHSSQPSSRMALPPSPLAMEYVNDFDLMKFEVKREPSEGR 133

  Fly   312 -GSASGALTPTCLPQVPSNGSGSSGG--GGGSGSGSG--------------GPGSVGGGSCVITR 359
             |..:.:|..|....||.:.:.|..|  |...|:..|              |.|...|.|.....
Human   134 PGPPTASLGSTPYSSVPPSPTFSEPGMVGATEGTRPGLEELYWLATLQQQLGAGEALGLSPEEAM 198

  Fly   360 AALQPCRPLSASSTRSSNNMSPRTCSGAYSNATLEDCLNDDMLTTLTVRELNKRLHGCPREEVVR 424
            ..||...|:...........||.. :|| .:..|.:..:|..|.:::|||||::|.||.|:|.:|
Human   199 ELLQGQGPVPVDGPHGYYPGSPEE-TGA-QHVQLAERFSDAALVSMSVRELNRQLRGCGRDEALR 261

  Fly   425 LKQKRRTLKNRGYAQNCRSKRLHQRHELEKANRVLNQDLHRLKLEYSRVCQERDALMQRLQRAAN 489
            |||:|||||||||||.||||||.||..||.....|...|..|:.|.:|:.:|||....|..|..:
Human   262 LKQRRRTLKNRGYAQACRSKRLQQRRGLEAERARLAAQLDALRAEVARLARERDLYKARCDRLTS 326

  Fly   490 GGVGAG 495
            .|.|:|
Human   327 SGPGSG 332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tj	NP_001260582.1	bZIP_Maf	397..486	CDD:427158	46/88 (52%)
		coiled coil	419..486	CDD:269866	36/66 (55%)
NRL	XP_011535103.2	Maf_N	169..203	CDD:462456	6/33 (18%)
		bZIP_Maf_large	256..325	CDD:269866	37/68 (54%)
		coiled coil	256..325	CDD:269866	37/68 (54%)