DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment tj and Mafa

DIOPT Version :10

Sequence 1:NP_001260582.1 Gene:tj / 35227 FlyBaseID:FBgn0000964 Length:555 Species:Drosophila melanogaster
Sequence 2:NP_919331.1 Gene:Mafa / 378435 MGIID:2673307 Length:359 Species:Mus musculus


Alignment Length:418 Identity:124/418 - (29%)
Similarity:163/418 - (38%) Gaps:155/418 - (37%)


- Green bases have known domain annotations that are detailed below.


  Fly   144 PGGVPSTPPETPPVVGSPTGSSSCPAQTYAHHYARTPGSSVSVSASAAAAAAASA---------- 198
            ||.:.|||..| |....|:..|.|         |.:||:........:||.|..|          
Mouse    47 PGSLSSTPLST-PCSSVPSSPSFC---------APSPGTGGGAGGGGSAAQAGGAPGPPSGGPGT 101

  Fly   199 -GAASVSAGLSHDMMWLTN-SIRADQQPLDLRPLPYPGSQEEAEEWDRQRDYALQAAAAHHHHHG 261
             |.||..|.| .|:.|::. ....:.:.|:|.|       |:|.|       ||..:..|..|||
Mouse   102 VGGASGKAVL-EDLYWMSGYQHHLNPEALNLTP-------EDAVE-------ALIGSGHHGAHHG 151

  Fly   262 QPLMQAQHHP--------------------------HGHGGHPHQVMLQQSKYPHHHHHHFHNLE 300
                  .|||                          |.||.| |......|.:.||||||.|   
Mouse   152 ------AHHPAAAAAYEAFRGQSFAGGGGADDMGAGHHHGAH-HTAHHHHSAHHHHHHHHHH--- 206

  Fly   301 LTPINMHSNSYGSASGALTPTCLPQVPSNGSGSSGGGGGSGSGSGGPGSVGGGSCVITRAALQPC 365
                                        .|||..|||.|.|.|                      
Mouse   207 ----------------------------GGSGHHGGGAGHGGG---------------------- 221

  Fly   366 RPLSASSTRSSNNMSPRTCSGAYSNATLEDCLNDDMLTTLTVRELNKRLHGCPREEVVRLKQKRR 430
                                ||..:..||:..:||.|.:::|||||::|.|..:|||:|||||||
Mouse   222 --------------------GAGHHVRLEERFSDDQLVSMSVRELNRQLRGFSKEEVIRLKQKRR 266

  Fly   431 TLKNRGYAQNCRSKRLHQRHELEKANRVLNQDLHRLKLEYSRVCQERDALMQRLQRAAN----GG 491
            |||||||||:||.||:.|||.||.....|...:.:||||..|:.:|||...::.::.|.    ||
Mouse   267 TLKNRGYAQSCRFKRVQQRHILESEKCQLQSQVEQLKLEVGRLAKERDLYKEKYEKLAGRGGPGG 331

  Fly   492 VGAGG-------ATAG-GDSQSSPEFYL 511
            .|..|       |.|| |.::.:|:|:|
Mouse   332 AGGAGFPREPSPAQAGPGAAKGAPDFFL 359

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tjNP_001260582.1 bZIP_Maf 397..486 CDD:427158 47/88 (53%)
coiled coil 419..486 CDD:269866 37/66 (56%)
MafaNP_919331.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 40..105 18/67 (27%)
Maf_N 111..142 CDD:462456 11/45 (24%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 172..226 24/127 (19%)
bZIP_Maf_large 255..323 CDD:269866 37/67 (55%)
coiled coil 255..323 CDD:269866 37/67 (55%)
Basic motif 260..285 20/24 (83%)
Leucine-zipper 288..309 7/20 (35%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 322..359 11/36 (31%)

Return to query results.
Submit another query.