DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tj and MAFF

DIOPT Version :9

Sequence 1:	NP_001260582.1	Gene:	tj / 35227	FlyBaseID:	FBgn0000964	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	NP_001155044.1	Gene:	MAFF / 23764	HGNCID:	6780	Length:	164	Species:	Homo sapiens

Alignment Length:	133	Identity:	53/133 - (39%)
Similarity:	73/133 - (54%)	Gaps:	14/133 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   367 PLSASSTRSSNNMSPRTCSGAYSNATLEDCLNDDMLTTLTVRELNKRLHGCPREEVVRLKQKRRT 431
            |||:.:.:....:|..|           ..|:|:.|..|:|||||:.|.|...|||.||||:|||
Human     5 PLSSKALKIKRELSENT-----------PHLSDEALMGLSVRELNRHLRGLSAEEVTRLKQRRRT 58

  Fly   432 LKNRGYAQNCRSKRLHQRHELEKANRVLNQDLHRLKLEYSRVCQERDAL---MQRLQRAANGGVG 493
            |||||||.:||.||:.|:.||:|....|.:::.:|..|.:.:..|.|||   .:.||..|.....
Human    59 LKNRGYAASCRVKRVCQKEELQKQKSELEREVDKLARENAAMRLELDALRGKCEALQGFARSVAA 123

  Fly   494 AGG 496
            |.|
Human   124 ARG 126

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tj	NP_001260582.1	bZIP_Maf	397..486	CDD:281170	44/91 (48%)
tj	NP_001260582.1	coiled coil	419..486	CDD:269866	33/69 (48%)
MAFF	NP_001155044.1	bZIP_Maf	24..115	CDD:308642	43/90 (48%)
		coiled coil	47..115	CDD:269865	32/67 (48%)
		Basic motif. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00978	51..76		18/24 (75%)
		PRK13729	78..>162	CDD:184281	15/49 (31%)
		Leucine-zipper. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00978	79..93		3/13 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	141..164
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143685
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4196
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1395389at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5055
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.780