Protein Alignment tj and Mafb

DIOPT Version :10

• Sequence 1: NP_001260582.1
• Gene: tj / 35227
• FlyBaseID: FBgn0000964
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_034788.1
• Gene: Mafb / 16658
• MGIID: 104555
• Length: 323
• Species: Mus musculus
• Alignment Length: 477
• Identity: 132/477 - (27%)
• Similarity: 183/477 - (38%)
• Gaps: 183/477 - (38%)

  Fly    53 PPQPVAVKWTTIHGDPTNPDDDPDSLPLS-GPEPAGAVEVSPSPHIKLRSFSGHHQWHMDERRLQ 116
            |..|:|:::.          :|.|.|... ..||.|..|....|.                .|||
Mouse    12 PTSPLAMEYV----------NDFDLLKFDVKKEPLGRAERPGRPC----------------TRLQ 50

  Fly   117 PLSPPPEQYGPLPGQAILVNTSSGAGVPGGVPSTPPETPPVVGSPTGSSSCPAQTYAHHYARTPG 181
            |                          .|.|.|||..| |....|:..|..|.:...|
Mouse    51 P--------------------------AGSVSSTPLST-PCSSVPSSPSFSPTEPKTH------- 81

  Fly   182 SSVSVSASAAAAAAASAGAASVSAGLSHDMMWL-TNSIRADQQPLDL------------RPLPYP 233
                                      ..|:.|: :|..:.:.:.|:|            .|:|.|
Mouse    82 --------------------------LEDLYWMASNYQQMNPEALNLTPEDAVEALIGSHPVPQP 120

  Fly   234 GSQEEAEEWDRQRDYALQAAAAHHHHHGQPLMQAQHHPHGHGGHPHQVM----LQQSKYPHHHHH 294
                 .:.:|..|       :||||||       .||||.|.|:|...:    |.|..:||||||
Mouse   121 -----LQSFDGFR-------SAHHHHH-------HHHPHPHHGYPGAGVTHDDLGQHAHPHHHHH 166

  Fly   295 HFHNLELTPINMHSNSYGSASGALTPTCLPQVPSNGSGSSGGGGGSGSGSGGPGSVGGGSCVITR 359
            |    :.:|         ..|.|.:|.  .|:|::..|.......:.:.:||.|||
Mouse   167 H----QASP---------PPSSAASPA--QQLPTSHPGPGPHATAAATAAGGNGSV--------- 207

  Fly   360 AALQPCRPLSASSTRSSNNMSPRTCSGAYSNATLEDCLNDDMLTTLTVRELNKRLHGCPREEVVR 424
                                              ||..:||.|.:::|||||:.|.|..::||:|
Mouse   208 ----------------------------------EDRFSDDQLVSMSVRELNRHLRGFTKDEVIR 238

  Fly   425 LKQKRRTLKNRGYAQNCRSKRLHQRHELEKANRVLNQDLHRLKLEYSRVCQERDALMQRLQRAAN 489
            |||||||||||||||:||.||:.|:|.||.....|.|.:.:||.|.||:.:||||...:.::.||
Mouse   239 LKQKRRTLKNRGYAQSCRYKRVQQKHHLENEKTQLIQQVEQLKQEVSRLARERDAYKVKCEKLAN 303

  Fly   490 GGVGAGGATAGGDSQSSPEFYL 511
            .|....|:|:  ||.|||||:|
Mouse   304 SGFREAGSTS--DSPSSPEFFL 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tj	NP_001260582.1	bZIP_Maf	397..486	CDD:427158	47/88 (53%)
		coiled coil	419..486	CDD:269866	37/66 (56%)
Mafb	NP_034788.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	34..78		19/86 (22%)
		Maf_N	80..113	CDD:462456	6/65 (9%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	116..210		40/170 (24%)
		bZIP_Maf_large	233..302	CDD:269866	37/68 (54%)
		coiled coil	233..302	CDD:269866	37/68 (54%)
		Basic motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978	238..263		20/24 (83%)
		Leucine-zipper. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978	266..287		8/20 (40%)