DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10026 and sec14l8

DIOPT Version :9

Sequence 1:	NP_609968.3	Gene:	CG10026 / 35226	FlyBaseID:	FBgn0032785	Length:	299	Species:	Drosophila melanogaster
Sequence 2:	NP_001093463.1	Gene:	sec14l8 / 558964	ZFINID:	ZDB-GENE-060526-180	Length:	395	Species:	Danio rerio

Alignment Length:	302	Identity:	65/302 - (21%)
Similarity:	119/302 - (39%)	Gaps:	70/302 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 GECPSSKDKVIEQFRNYILEHNECQPHRSDAKYLEKFLRARYWKIENSYKLLCSYYRFREQNK-- 98
            |:....:.:.:.|||..:.:.....|.:|| .:|.::||||.:.::.|..:|..:..||:..|
Zfish     6 GDLSVKQAEALAQFREKVQDVLPQCPSQSD-HFLLRWLRARNFNLQKSEAMLRKHIEFRKHMKVD 69

  Fly    99 -----------------------------SFYEKVRPLD---LRHVGQSDILTVTPYRDQHGHRI 131
                                         .:|:.:.|||   |.|......|..:..||
Zfish    70 TITTEWQVPEVIDKYLSGGMCGHDREGSPVWYDVIGPLDPKGLMHSASKQDLIKSKVRD------ 128

  Fly   132 LIYRFGLWRPNQVTVDDIFRATIVLQELG-SLEPISQIVGGVGIFDLKDLGLEHILHLSPSVAQK 195
                      .::...|..|.:   :.|| ::|.|:.      ::|.:.||::|:...:.....:
Zfish   129 ----------CEILQKDCDRQS---ERLGRNIESITM------VYDCEGLGMKHLYKPAIETYGE 174

  Fly   196 MIALLVTSMPIRTSALHIVNQNWVFNAAFKIFKPFLNAAMREKLYIHGSDMTS-LHKHINPEHLP 259
            ::.:...:.|.....|.::....:|..|:.:.|.||:...|.|:.:.||:... |.|:|:||.||
Zfish   175 VLTMFEDNYPEGLKRLFVIKAPKLFPVAYNLVKHFLSEDTRRKVIVLGSNWQEVLQKYIDPEELP 239

  Fly   260 KRYGGLHED--------YSYTLWLDMLKEQCSGNSIQKDMEQ 293
            ..|||...|        ...|...::.|.....:||:.|.||
Zfish   240 AYYGGKLTDPDGDPKCRTRITFGSEIPKSYYVRDSIKVDYEQ 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10026	NP_609968.3	CRAL_TRIO_N	43..90	CDD:215024	13/46 (28%)
CG10026	NP_609968.3	SEC14	112..265	CDD:238099	33/154 (21%)
sec14l8	NP_001093463.1	CRAL_TRIO_N	13..59	CDD:215024	13/46 (28%)
		SEC14	78..246	CDD:214706	40/192 (21%)
		GOLD_2	304..382	CDD:290608
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810