DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10026 and Clvs2

DIOPT Version :9

Sequence 1:	NP_609968.3	Gene:	CG10026 / 35226	FlyBaseID:	FBgn0032785	Length:	299	Species:	Drosophila melanogaster
Sequence 2:	NP_780657.1	Gene:	Clvs2 / 215890	MGIID:	2443223	Length:	327	Species:	Mus musculus

Alignment Length:	252	Identity:	69/252 - (27%)
Similarity:	129/252 - (51%)	Gaps:	2/252 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 PEHIRRLAQEQGECPSSKDKVIEQFRNYILEHNECQPHRSDAKYLEKFLRARYWKIENSYKLLCS 89
            ||.:.:...|..|.|.:..:.|::.|:.::...:....|:|..::.:|||||.:....:::||..
Mouse    10 PETLEKARLELNENPDTLHQDIQEVRDMVITRPDIGFLRTDDAFILRFLRARKFHHFEAFRLLAQ 74

  Fly    90 YYRFREQNKSFYEKVRPLD--LRHVGQSDILTVTPYRDQHGHRILIYRFGLWRPNQVTVDDIFRA 152
            |:.:|:||...::..:..|  ::...:..........|.:|.:||:.....|..::.|:.||.||
Mouse    75 YFEYRQQNLDMFKSFKATDPGIKQALKDGFPGGLANLDHYGRKILVLFAANWDQSRYTLVDILRA 139

  Fly   153 TIVLQELGSLEPISQIVGGVGIFDLKDLGLEHILHLSPSVAQKMIALLVTSMPIRTSALHIVNQN 217
            .::..|....:|..|:.|.|.|.|..:...:....|:|::.:..|..|..|.|.|...:|.|||.
Mouse   140 ILLSLEAMIEDPELQVNGFVLIIDWSNFTFKQASKLTPNMLRLAIEGLQDSFPARFGGIHFVNQP 204

  Fly   218 WVFNAAFKIFKPFLNAAMREKLYIHGSDMTSLHKHINPEHLPKRYGGLHEDYSYTLW 274
            |..:|.:.:.:|||....|:::::||:::.|||:.|:||.||..:||:...|....|
Mouse   205 WYIHALYTVIRPFLKEKTRKRIFLHGNNLNSLHQLIHPEILPSEFGGMLPPYDMGTW 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10026	NP_609968.3	CRAL_TRIO_N	43..90	CDD:215024	11/46 (24%)
CG10026	NP_609968.3	SEC14	112..265	CDD:238099	45/152 (30%)
Clvs2	NP_780657.1	CRAL_TRIO_N	29..75	CDD:215024	11/45 (24%)
		SEC14	106..251	CDD:238099	44/144 (31%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	289..327
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D559280at33208
OrthoFinder	1	1.000	-	-		FOG0000233
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X106
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.820