DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10026 and hpo-28

DIOPT Version :9

Sequence 1:	NP_609968.3	Gene:	CG10026 / 35226	FlyBaseID:	FBgn0032785	Length:	299	Species:	Drosophila melanogaster
Sequence 2:	NP_498232.3	Gene:	hpo-28 / 175798	WormBaseID:	WBGene00015148	Length:	567	Species:	Caenorhabditis elegans

Alignment Length:	264	Identity:	48/264 - (18%)
Similarity:	102/264 - (38%)	Gaps:	72/264 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 IEQFRNYILE-------HNECQPH--RSDAKYLEKFLRARYWKIENSYKLLCSYYRFREQNKSFY 101
            :.:.|:.||:       |.....|  |.:..:|::||.:..:.::.:|.::....::|   ::|
Worm    27 VHELRSRILQDPAISVKHLSDDVHRIRHEDWWLDRFLGSVNYDVDIAYAIMLECLKWR---RNF- 87

  Fly   102 EKVRPLDLRHVGQSDILTVTPYRDQ-----HG------HRILI----YRFGLWRPNQVTVDDIFR 151
                     .|.:..:|::.|..|.     ||      |.:.|    |:.|         ||.|.
Worm    88 ---------EVDRISLLSLKPLLDNQLMYLHGKDLQNRHMLWIMMNKYKNG---------DDGFE 134

  Fly   152 ATIVL------QELGSLEPISQIVG--GVGIFDLKDLGLEHILHLSPSVAQKMI-ALLVTSMPIR 207
            .....      .|....:|::..:.  |.|:.::....::.|:|.|.......| ::|:...|.
Worm   135 KLFTFWIERHYMEYKGCQPLTVFIDMTGTGLKNMSFDAMKFIIHSSKYYYPNSIESILIFENPA- 198

  Fly   208 TSALHIVNQNWVFNAAFKIFKPFLN---AAMREKLYIHGSDMTSLHKHINPEHLPKRYGGLHEDY 269
                       :.||::|:...:|.   |:.|..|....:.::..| ::...||.:..||. :.:
Worm   199 -----------ILNASWKVIGSWLESSAASQRHDLLTFVTKLSVTH-YVPKSHLLEHQGGT-DTF 250

  Fly   270 SYTL 273
            .:|:
Worm   251 KFTM 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10026	NP_609968.3	CRAL_TRIO_N	43..90	CDD:215024	10/52 (19%)
CG10026	NP_609968.3	SEC14	112..265	CDD:238099	34/179 (19%)
hpo-28	NP_498232.3	SEC14	105..247	CDD:238099	30/163 (18%)
hpo-28	NP_498232.3	Motile_Sperm	<381..460	CDD:279029
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910