DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10026 and ctg-2

DIOPT Version :9

Sequence 1:	NP_609968.3	Gene:	CG10026 / 35226	FlyBaseID:	FBgn0032785	Length:	299	Species:	Drosophila melanogaster
Sequence 2:	NP_001254156.1	Gene:	ctg-2 / 174360	WormBaseID:	WBGene00011756	Length:	408	Species:	Caenorhabditis elegans

Alignment Length:	277	Identity:	61/277 - (22%)
Similarity:	101/277 - (36%)	Gaps:	66/277 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 RLAQEQGECPSSKDKVIEQFRNYILEHNECQPHRSDAKYLEKFLRARYWKI--ENSYKLLCSYYR 92
            |::...||...|..|::::.|..|  |.|.:..:   :|.:.|...| |.|  :....::....:
Worm    12 RMSTSTGEITESDRKLLDELRKRI--HKELELVK---EYDDDFSLMR-WLIGWDRKIDVVVPKIK 70

  Fly    93 FREQNKSFYEKVRPLDLRHVGQSDILTV-----------TPYRDQHGHRILIYRFGLWRPNQVTV 146
            |         .:|.:....:.|.|:.|:           .|.|...|..|     ||...|.|..
Worm    71 F---------SLRAIHALGLDQEDLSTLEKVAQKCDDCSVPLRYLPGSLI-----GLDHENNVVS 121

  Fly   147 ------------------DDIFRATI-----VLQELGSLE-----PISQIVGGVGIFDLKDLGLE 183
                              .|::|..|     |:|.:..:|     |:...|    ||||..|.:.
Worm   122 LQMIGHLDAAGLMPATRNSDLYRMRIAESEGVMQIIRKMEKEQGKPLGTSV----IFDLDGLSMV 182

  Fly   184 HILHLSPSVAQKMIALLVTSMPIRTSALHIVNQNWVFNAAFKIFKPFLNAAMREKLYIHGSDMTS 248
            .|...:..|...|::.|....|.....:.|||........:.:..|.|....::|:.|.|:|...
Worm   183 QIDLAALKVVTTMLSQLQEMFPDVIRKIFIVNTPTFIQVLWSMISPCLAKQTQQKVKILGNDWKQ 247

  Fly   249 -LHKHINPEHLPKRYGG 264
             |.::|..|.|.:|:||
Worm   248 HLKENIGEEVLFERWGG 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10026	NP_609968.3	CRAL_TRIO_N	43..90	CDD:215024	10/48 (21%)
CG10026	NP_609968.3	SEC14	112..265	CDD:238099	45/193 (23%)
ctg-2	NP_001254156.1	SEC14	98..267	CDD:214706	42/176 (24%)
ctg-2	NP_001254156.1	EMP24_GP25L	331..>405	CDD:279450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910