DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10026 and Sec14l4

DIOPT Version :9

Sequence 1:	NP_609968.3	Gene:	CG10026 / 35226	FlyBaseID:	FBgn0032785	Length:	299	Species:	Drosophila melanogaster
Sequence 2:	NP_666125.1	Gene:	Sec14l4 / 103655	MGIID:	2144095	Length:	403	Species:	Mus musculus

Alignment Length:	259	Identity:	63/259 - (24%)
Similarity:	107/259 - (41%)	Gaps:	43/259 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 GECPSSKDKVIEQFRNYILEHNECQPHRSDAKYLEKFLRARYWKIENSYKLLCSYYRFREQNKSF 100
            |:....:.:.:.:||..:.:.....| ::|..:|.::||||.:.::.|..:|..:..||.|..
Mouse     6 GDLSPQQQEALARFRETLQDLLPTLP-KADDYFLLRWLRARNFDLKKSEDMLRKHVEFRNQQN-- 67

  Fly   101 YEKVRPLDLRHVGQSDILT--------------VTPYRDQHGHRILIYRFGLWRPN----QVTVD 147
                  ||       .|||              ::.| |..|..:.....|...|.    ..:..
Mouse    68 ------LD-------QILTWQAPEVIQLYDSGGLSGY-DYEGCPVWFDIIGTMDPKGLFMSASKQ 118

  Fly   148 DIFRATIVLQE--LGSLEPISQIVGG-----VGIFDLKDLGLEHILHLSPSVAQKMIALLVTSMP 205
            |:.|..|.:.|  |...|..||.:|.     |.:||::.|.|.|:...:..|.|:..|:|..:.|
Mouse   119 DMIRKRIKVCEMLLHECELQSQKLGRKIERMVMVFDMEGLSLRHLWKPAVEVYQQFFAILEANYP 183

  Fly   206 IRTSALHIVNQNWVFNAAFKIFKPFLNAAMREKLYIHGSD-MTSLHKHINPEHLPKRYGGLHED 268
            .....|.|:....:|..||.:.|.|:....::|:.|.|.: ...|.|.::|:.||..:||...|
Mouse   184 ETVKNLIIIRAPKLFPVAFNLVKSFMGEETQKKIVILGGNWKQELVKFVSPDQLPVEFGGTMTD 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10026	NP_609968.3	CRAL_TRIO_N	43..90	CDD:215024	11/46 (24%)
CG10026	NP_609968.3	SEC14	112..265	CDD:238099	44/178 (25%)
Sec14l4	NP_666125.1	CRAL_TRIO_N	13..59	CDD:215024	11/46 (24%)
		SEC14	77..244	CDD:214706	41/167 (25%)
		GOLD_2	284..379	CDD:290608
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810