DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment RanGAP and AT3G06000

DIOPT Version :9

Sequence 1:	NP_001260578.1	Gene:	RanGAP / 35223	FlyBaseID:	FBgn0003346	Length:	596	Species:	Drosophila melanogaster
Sequence 2:	NP_187251.1	Gene:	AT3G06000 / 819771	AraportID:	AT3G06000	Length:	211	Species:	Arabidopsis thaliana

Alignment Length:	197	Identity:	47/197 - (23%)
Similarity:	81/197 - (41%)	Gaps:	41/197 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   184 SRNRLEDAGATEMATAFQ-TLKTFEEIVLEQNSIYIEGVEALAESFKHNPHLRVLNMNDNTLKSE 247
            |...||:.||..:..|.: :..:.:.|.:..|:|..|...|:|.......||:.||:::|.||.|
plant    45 SYTNLENGGAIALVNALKNSAPSLQVIEMAGNNITYEAATAIAVCLAAKRHLKKLNLSENDLKDE 109

  Fly   248 GAEKIAEALPFLPLLREMSFGDCLIKTNGAYHFGEALERGNERLEVIDLGFNEINSDGGLVLVNA 312
            |..:|.:::.                              :..||.:|:.:|::..:|.|.|...
plant   110 GCVEIVKSME------------------------------DWELEYVDMSYNDLRREGALRLARV 144

  Fly   313 MGNKPKLRILNLDGNSFGEEGSEKIISEMSKLPTAAALQPFQHQEEEDLEDEYQADKQDADYEEE 377
            :..|...::||:|||....:|.|:|....:..|  ..|.|..       ::.|..|..| |..|.
plant   145 VVKKGSFKMLNIDGNMISLKGIEEIKVIFTNCP--KLLGPLD-------KNVYNVDDDD-DLREN 199

  Fly   378 EE 379
            :|
plant   200 DE 201

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RanGAP	NP_001260578.1	leucine-rich repeat	45..77	CDD:275380
		LRR_RI	50..337	CDD:238064	37/153 (24%)
		leucine-rich repeat	78..109	CDD:275380
		leucine-rich repeat	110..139	CDD:275380
		leucine-rich repeat	140..167	CDD:275380
		leucine-rich repeat	178..205	CDD:275380	6/21 (29%)
		leucine-rich repeat	206..233	CDD:275380	6/26 (23%)
		leucine-rich repeat	234..261	CDD:275380	9/26 (35%)
		leucine-rich repeat	262..290	CDD:275380	0/27 (0%)
AT3G06000	NP_187251.1	LRR_RI	<33..>170	CDD:423007	37/154 (24%)
		leucine-rich repeat	39..67	CDD:275380	6/21 (29%)
		leucine-rich repeat	68..95	CDD:275380	6/26 (23%)
		leucine-rich repeat	96..122	CDD:275380	9/55 (16%)
		leucine-rich repeat	123..143	CDD:275380	7/19 (37%)
		leucine-rich repeat	144..178	CDD:275380	10/35 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5238
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1357476at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3162
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820