Protein Alignment RanGAP and rna1

DIOPT Version :10

• Sequence 1: NP_476712.1
• Gene: RanGAP / 35223
• FlyBaseID: FBgn0003346
• Length: 596
• Species: Drosophila melanogaster
• Sequence 2: NP_594833.1
• Gene: rna1 / 2541863
• PomBaseID: SPAC22E12.07
• Length: 386
• Species: Schizosaccharomyces pombe
• Alignment Length: 389
• Identity: 136/389 - (34%)
• Similarity: 197/389 - (50%)
• Gaps: 22/389 - (5%)

  Fly    20 SFENKVLSWN--TAADVQDVVDALNKQTTVHYLNLDGNTLGVEAAKAIGEGLKRHPEFRKALWKN 82
            |.|.|.|..:  |..|.:.|...|.:..:|..:.|.|||:|.|||:.:.|.:....:...|.:.:
pombe     5 SIEGKSLKLDAITTEDEKSVFAVLLEDDSVKEIVLSGNTIGTEAARWLSENIASKKDLEIAEFSD 69

  Fly    83 MFTGRLISEIPEALKHLGAALIVAGAKLTVLDLSDNALGPNGMRGLEELL--RSPVCYSLQELLL 145
            :||||:..||||||:.|..||:.. .||..:.|||||.||.....|.:.|  .:|    |:.|.|
pombe    70 IFTGRVKDEIPEALRLLLQALLKC-PKLHTVRLSDNAFGPTAQEPLIDFLSKHTP----LEHLYL 129

  Fly   146 CNCGLGPEGGSMLSRALIDLHANANKAGFPLQLRVFIGSRNRLEDAGATEMATAFQTLKTFEEIV 210
            .|.||||:.|:.::|||.:|..|......| .||..|..|||||:....|.|..||:.:....:.
pombe   130 HNNGLGPQAGAKIARALQELAVNKKAKNAP-PLRSIICGRNRLENGSMKEWAKTFQSHRLLHTVK 193

  Fly   211 LEQNSIYIEGVE-ALAESFKHNPHLRVLNMNDNTLKSEGAEKIAEALPFLPLLREMSFGDCLIKT 274
            :.||.|..||:| .|.|...:...|:||::.|||....|:..:|.||...|.|||:...|||:..
pombe   194 MVQNGIRPEGIEHLLLEGLAYCQELKVLDLQDNTFTHLGSSALAIALKSWPNLRELGLNDCLLSA 258

  Fly   275 NGAYHFGEALER-GNERLEVIDLGFNEINSDGGLVLVNAMGNK-PKLRILNLDGNSFGEEGSEKI 337
            .||....:|..: .|..|:.:.|.:|||..|....|...:..| |.|..|.|:||.|.||  :.:
pombe   259 RGAAAVVDAFSKLENIGLQTLRLQYNEIELDAVRTLKTVIDEKMPDLLFLELNGNRFSEE--DDV 321

  Fly   338 ISEMSKLPTAAALQPFQHQEEEDLED-EYQADKQDADYEEEEEVHEHANDTTEEADEDSE-GDE 399
            :.|:.::.:...     ..|.::|:| |...|:::.|.|||.|......:|:||..||.| .||
pombe   322 VDEIREVFSTRG-----RGELDELDDMEELTDEEEEDEEEEAESQSPEPETSEEEKEDKELADE 380

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RanGAP	NP_476712.1	leucine-rich repeat	45..77	CDD:275380	10/31 (32%)
		LRR_RI	50..337	CDD:238064	108/291 (37%)
		leucine-rich repeat	78..109	CDD:275380	14/30 (47%)
		leucine-rich repeat	110..139	CDD:275380	11/30 (37%)
		leucine-rich repeat	140..167	CDD:275380	13/26 (50%)
		leucine-rich repeat	178..205	CDD:275380	12/26 (46%)
		leucine-rich repeat	206..233	CDD:275380	8/27 (30%)
		leucine-rich repeat	234..261	CDD:275380	10/26 (38%)
		leucine-rich repeat	262..290	CDD:275380	10/28 (36%)
rna1	NP_594833.1	LRR_RI	3..332	CDD:238064	118/334 (35%)
		leucine-rich repeat	96..120	CDD:275380	10/23 (43%)
		leucine-rich repeat	124..145	CDD:275380	9/20 (45%)
		leucine-rich repeat	161..188	CDD:275380	12/26 (46%)
		leucine-rich repeat	189..217	CDD:275380	8/27 (30%)
		leucine-rich repeat	218..245	CDD:275380	10/26 (38%)
		leucine-rich repeat	246..273	CDD:275380	9/26 (35%)