Protein Alignment RanGAP and LOC100333051

DIOPT Version :9

• Sequence 1: NP_001260578.1
• Gene: RanGAP / 35223
• FlyBaseID: FBgn0003346
• Length: 596
• Species: Drosophila melanogaster
• Sequence 2: XP_021326497.1
• Gene: LOC100333051 / 100333051
• -ID: -
• Length: 685
• Species: Danio rerio
• Alignment Length: 407
• Identity: 102/407 - (25%)
• Similarity: 161/407 - (39%)
• Gaps: 100/407 - (24%)

  Fly    12 QLGQEQGISFENKVLSWNTAADVQDVVDALNKQTTVHYLNLDGNTLGVEAAKA-IGEGLKRHPEF 75
            |...|:.::.|:.:|.....|..|     |.|...:.| ..|....|::.|:| :..||... .|
Zfish   311 QKDYEEKLTDEDMILKLGKVAFQQ-----LMKGNIIFY-EEDLRECGIDVAEASVYSGLCTQ-IF 368

  Fly    76 RKALWKNMFTGRLISEIPEALKHLGAALIVAGAKLTVLD-----------------LSD----NA 119
            |:..  .::.|::.|.:..:::...|||.|   .|:.::                 :.|    |:
Zfish   369 REEF--GLYQGKVFSFVHLSIQEHLAALYV---HLSCINNNRDEFEEINKQSLWSKVKDHFHFNS 428

  Fly   120 LGPNGMRGLEELLRSPVCYSLQELLLCNCGLGPEGGSMLSRALIDLHANANKAGFPLQLRVFIGS 184
            |.|..:..|..||  .:.|.|..  |.:|||.....:.|:.||     .:|    |..|||...|
Zfish   429 LKPVSLFSLHHLL--SIIYCLHR--LSDCGLTEMDCAALASAL-----RSN----PSDLRVLNLS 480

  Fly   185 RNRLEDAGATEMATAFQTLKTFEEIVLEQNSIYIEGVEALAESFKHNP-HLRVLNMNDNTLKSEG 248
            ||.|.|:.:...|.........|::.|....:..||..|||.:.|.|| |||.||:::|
Zfish   481 RNILVDSVSLLSAVLEDPCSKLEKLWLRYCDLTDEGCAALASALKSNPEHLRDLNLSEN------ 539

  Fly   249 AEKIAEALPFLPLLREMSFGDCLIKTNGAYHFG----------EALERGNERLEVIDLGFNEIN- 302
              |:.:::..|..:.|..  .|.:||...|:.|          .||....|.|..:||..|::.
Zfish   540 --KLGDSVTLLSAVLEDP--HCKLKTLWLYNCGLTDEGCAALALALRSNPEHLRDLDLSVNKLRD 600

  Fly   303 ----------------------SDGGL------VLVNAMGNKPK-LRILNLDGNSFGEEGSEKII 338
                                  ||.||      .|.:|:.:.|: |..|||..|..| |...|::
Zfish   601 SGIKLLSPLLEDPHCKLEKLWLSDCGLTDEGCAALASALRSNPEHLTELNLSKNKLG-ESDVKLL 664

  Fly   339 SEMSKLPTAAALQPFQH 355
            |:: |..|...|:.|.:
Zfish   665 SDL-KDDTHYKLKKFNY 680

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RanGAP	NP_001260578.1	leucine-rich repeat	45..77	CDD:275380	8/32 (25%)
		LRR_RI	50..337	CDD:238064	87/349 (25%)
		leucine-rich repeat	78..109	CDD:275380	6/30 (20%)
		leucine-rich repeat	110..139	CDD:275380	8/49 (16%)
		leucine-rich repeat	140..167	CDD:275380	8/26 (31%)
		leucine-rich repeat	178..205	CDD:275380	9/26 (35%)
		leucine-rich repeat	206..233	CDD:275380	10/27 (37%)
		leucine-rich repeat	234..261	CDD:275380	7/26 (27%)
		leucine-rich repeat	262..290	CDD:275380	8/37 (22%)
LOC100333051	XP_021326497.1	FISNA	1..67	CDD:316956
		NACHT	78..245	CDD:310381
		LRR_RI	423..667	CDD:330982	73/267 (27%)
		leucine-rich repeat	474..501	CDD:275380	9/26 (35%)
		leucine-rich repeat	502..526	CDD:275380	7/23 (30%)
		leucine-rich repeat	531..558	CDD:275380	8/36 (22%)
		leucine-rich repeat	559..587	CDD:275380	6/27 (22%)
		leucine-rich repeat	588..616	CDD:275380	4/27 (15%)
		leucine-rich repeat	617..645	CDD:275380	7/27 (26%)
		leucine-rich repeat	646..667	CDD:275380	9/21 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1357476at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010