DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab9 and Rab9b

DIOPT Version :9

Sequence 1:	NP_609966.1	Gene:	Rab9 / 35221	FlyBaseID:	FBgn0032782	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	NP_795945.1	Gene:	Rab9b / 319642	MGIID:	2442454	Length:	201	Species:	Mus musculus

Alignment Length:	207	Identity:	109/207 - (52%)
Similarity:	142/207 - (68%)	Gaps:	13/207 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 KSKLLKVVILGDGGVGKSALLTRFVANRYEENNFHTIGVEFMNKDIVVDGERYTLQIWDTAGQER 73
            ||.||||::|||||||||:|:.|:|.|:::...||||||||:|:|:.|||...||||||||||||
Mouse     4 KSLLLKVILLGDGGVGKSSLMNRYVTNKFDSQAFHTIGVEFLNRDLEVDGRFVTLQIWDTAGQER 68

  Fly    74 FRALRTPFYRGSDICLLCYALDDRDSLKGLGVWRNEFLNYADV-DQDKFPFIVVGNKNDIPAQKR 137
            |::||||||||:|.|||.:::|||.|.:.||.|:.||:.|||| |.|.|||:|:|||.|  .:.|
Mouse    69 FKSLRTPFYRGADCCLLTFSVDDRQSFENLGNWQKEFIYYADVKDPDHFPFVVLGNKVD--KEDR 131

  Fly   138 QVSSDAVQQWCAEQKVACHIETSSKAATNVTDAFVLGLRQWRHMECVAEAELRQH---GDTIDLT 199
            ||:::..|.||.|.....::|||:|..||||.||...:||     .:|..|..:|   |.||||.
Mouse   132 QVTTEEAQAWCMENGNYPYLETSAKDDTNVTVAFEEAVRQ-----VLAVEEQLEHCMLGHTIDLN 191

  Fly   200 RPIRLVQRRICC 211
            ...:....  ||
Mouse   192 SGSKASSS--CC 201

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab9	NP_609966.1	Rab9	8..178	CDD:206697	98/169 (58%)
Rab9	NP_609966.1	Ras	14..177	CDD:278499	93/163 (57%)
Rab9b	NP_795945.1	Rab9	3..172	CDD:206697	99/174 (57%)
Rab9b	NP_795945.1	Effector region. /evidence=ECO:0000250	36..44		6/7 (86%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	196	1.000	Domainoid score	I3124
eggNOG	1	0.900	-	-		E1_KOG0394
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3136
Inparanoid	1	1.050	206	1.000	Inparanoid score	I3712
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52476
OrthoDB	1	1.010	-	-		D1172019at2759
OrthoFinder	1	1.000	-	-		FOG0004055
OrthoInspector	1	1.000	-	-		oto92862
orthoMCL	1	0.900	-	-		OOG6_105995
Panther	1	1.100	-	-	LDO	PTHR47981
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5468
SonicParanoid	1	1.000	-	-		X2801
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.870