Protein Alignment RtcB and RTCB

DIOPT Version :9

• Sequence 1: NP_609965.1
• Gene: RtcB / 35220
• FlyBaseID: FBgn0032781
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_055121.1
• Gene: RTCB / 51493
• HGNCID: 26935
• Length: 505
• Species: Homo sapiens
• Alignment Length: 503
• Identity: 430/503 - (85%)
• Similarity: 464/503 - (92%)
• Gaps: 0/503 - (0%)

  Fly     4 RPYNDELRYLEKVSDHCWRIKKGFQPNMNVEGCFYVNSRLERLMLEELKNSCRPGAVGGFLPGVK 68
            |.|||||::|||::.:||||||||.|||.|||.||||..||:||.|||:|:||.|.||||||.:|
Human     3 RSYNDELQFLEKINKNCWRIKKGFVPNMQVEGVFYVNDALEKLMFEELRNACRGGGVGGFLPAMK 67

  Fly    69 QIANVAALPGIVGRSIGLPDIHSGYGFAIGNMAAFDMNDPLSVVSPGGVGFDINCGVRLLRTNLY 133
            ||.|||||||||.|||||||:|||||||||||||||||||.:||||||||||||||||||||||.
Human    68 QIGNVAALPGIVHRSIGLPDVHSGYGFAIGNMAAFDMNDPEAVVSPGGVGFDINCGVRLLRTNLD 132

  Fly   134 EKDVQPVKEQLAQSLFDHIPVGVGSKGIIPMNARDLEEALEMGMDWSLREGYVWAEDKEHCEEYG 198
            |.|||||||||||::||||||||||||:|||||:|||||||||:||||||||.||||||||||||
Human   133 ESDVQPVKEQLAQAMFDHIPVGVGSKGVIPMNAKDLEEALEMGVDWSLREGYAWAEDKEHCEEYG 197

  Fly   199 RMLNADPAKVSMRAKKRGLPQLGTLGAGNHYAEIQVVDEIYDKWSASKMGIEEKGQVVVMIHSGS 263
            |||.|||.|||.||||||||||||||||||||||||||||:::::|.||||:.||||.|||||||
Human   198 RMLQADPNKVSARAKKRGLPQLGTLGAGNHYAEIQVVDEIFNEYAAKKMGIDHKGQVCVMIHSGS 262

  Fly   264 RGFGHQVATDALVQMEKAMKRDKIETNDRQLACARINSVEGQDYLKAMAAAANFAWVNRSSMTFL 328
            ||.||||||||||.||||||||||..||||||||||.|.|||||||.||||.|:|||||||||||
Human   263 RGLGHQVATDALVAMEKAMKRDKIIVNDRQLACARIASPEGQDYLKGMAAAGNYAWVNRSSMTFL 327

  Fly   329 TRQAFAKMFNTTPDDLDMHVIYDVSHNIAKVENHMVDGKERKLLVHRKGSTRAFPPHHPLIPVDY 393
            |||||||:|||||||||:||||||||||||||.|:||||||.|||||||||||||||||||.|||
Human   328 TRQAFAKVFNTTPDDLDLHVIYDVSHNIAKVEQHVVDGKERTLLVHRKGSTRAFPPHHPLIAVDY 392

  Fly   394 QLTGQPVLVGGTMGTCSYVLTGTEQGMQETFGSTCHGAGRALSRAKSRRNLDYKDVLDKLDQLGI 458
            ||||||||:||||||||||||||||||.||||:|||||||||||||||||||::||||||..:||
Human   393 QLTGQPVLIGGTMGTCSYVLTGTEQGMTETFGTTCHGAGRALSRAKSRRNLDFQDVLDKLADMGI 457

  Fly   459 AIRVASPKLVMEEAPESYKDVTDVVDTCHAAGISKKCIKMRPIAVIKG 506
            |||||||||||||||||||:|||||:|||.||||||.||:||||||||
Human   458 AIRVASPKLVMEEAPESYKNVTDVVNTCHDAGISKKAIKLRPIAVIKG 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RtcB	NP_609965.1	RtcB	67..506	CDD:224604	384/438 (88%)
		RtcB	67..506	CDD:279481	384/438 (88%)
RTCB	NP_055121.1	RtcB	68..505	CDD:395906	383/436 (88%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165159383
Domainoid	1	1.000	784	1.000	Domainoid score	I77
eggNOG	1	0.900	-	-		E1_COG1690
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H36344
Inparanoid	1	1.050	883	1.000	Inparanoid score	I399
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60604
OrthoDB	1	1.010	-	-		D203128at33208
OrthoFinder	1	1.000	-	-		FOG0004814
OrthoInspector	1	1.000	-	-		oto90578
orthoMCL	1	0.900	-	-		OOG6_101445
Panther	1	1.100	-	-	LDO	PTHR11118
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2780
SonicParanoid	1	1.000	-	-		X3956
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800