DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment RtcB and Rtcb

DIOPT Version :9

Sequence 1:	NP_609965.1	Gene:	RtcB / 35220	FlyBaseID:	FBgn0032781	Length:	506	Species:	Drosophila melanogaster
Sequence 2:	NP_663397.1	Gene:	Rtcb / 28088	MGIID:	106379	Length:	505	Species:	Mus musculus

Alignment Length:	503	Identity:	429/503 - (85%)
Similarity:	464/503 - (92%)	Gaps:	0/503 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 RPYNDELRYLEKVSDHCWRIKKGFQPNMNVEGCFYVNSRLERLMLEELKNSCRPGAVGGFLPGVK 68
            |.|||||::|:|::.:||||||||.|||.|||.||||..||:||.|||:|:||.|.||||||.:|
Mouse     3 RNYNDELQFLDKINKNCWRIKKGFVPNMQVEGVFYVNDALEKLMFEELRNACRGGGVGGFLPAMK 67

  Fly    69 QIANVAALPGIVGRSIGLPDIHSGYGFAIGNMAAFDMNDPLSVVSPGGVGFDINCGVRLLRTNLY 133
            ||.|||||||||.|||||||:|||||||||||||||||||.:||||||||||||||||||||||.
Mouse    68 QIGNVAALPGIVHRSIGLPDVHSGYGFAIGNMAAFDMNDPEAVVSPGGVGFDINCGVRLLRTNLD 132

  Fly   134 EKDVQPVKEQLAQSLFDHIPVGVGSKGIIPMNARDLEEALEMGMDWSLREGYVWAEDKEHCEEYG 198
            |.|||||||||||::||||||||||||:|||||:|||||||||:||||||||.||||||||||||
Mouse   133 ESDVQPVKEQLAQAMFDHIPVGVGSKGVIPMNAKDLEEALEMGVDWSLREGYAWAEDKEHCEEYG 197

  Fly   199 RMLNADPAKVSMRAKKRGLPQLGTLGAGNHYAEIQVVDEIYDKWSASKMGIEEKGQVVVMIHSGS 263
            |||.|||.|||.||||||||||||||||||||||||||||:::::|.||||:.||||.|||||||
Mouse   198 RMLQADPNKVSPRAKKRGLPQLGTLGAGNHYAEIQVVDEIFNEYAAKKMGIDHKGQVCVMIHSGS 262

  Fly   264 RGFGHQVATDALVQMEKAMKRDKIETNDRQLACARINSVEGQDYLKAMAAAANFAWVNRSSMTFL 328
            ||.||||||||||.||||||||||..||||||||||.|.|||||||.||||.|:|||||||||||
Mouse   263 RGLGHQVATDALVAMEKAMKRDKIIVNDRQLACARIASPEGQDYLKGMAAAGNYAWVNRSSMTFL 327

  Fly   329 TRQAFAKMFNTTPDDLDMHVIYDVSHNIAKVENHMVDGKERKLLVHRKGSTRAFPPHHPLIPVDY 393
            |||||||:|||||||||:||||||||||||||.|:||||||.|||||||||||||||||||.|||
Mouse   328 TRQAFAKVFNTTPDDLDLHVIYDVSHNIAKVEQHVVDGKERTLLVHRKGSTRAFPPHHPLIAVDY 392

  Fly   394 QLTGQPVLVGGTMGTCSYVLTGTEQGMQETFGSTCHGAGRALSRAKSRRNLDYKDVLDKLDQLGI 458
            ||||||||:||||||||||||||||||.||||:|||||||||||||||||||::||||||..:||
Mouse   393 QLTGQPVLIGGTMGTCSYVLTGTEQGMTETFGTTCHGAGRALSRAKSRRNLDFQDVLDKLADMGI 457

  Fly   459 AIRVASPKLVMEEAPESYKDVTDVVDTCHAAGISKKCIKMRPIAVIKG 506
            |||||||||||||||||||:|||||:|||.||||||.||:||||||||
Mouse   458 AIRVASPKLVMEEAPESYKNVTDVVNTCHDAGISKKAIKLRPIAVIKG 505

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RtcB	NP_609965.1	RtcB	67..506	CDD:224604	384/438 (88%)
RtcB	NP_609965.1	RtcB	67..506	CDD:279481	384/438 (88%)
Rtcb	NP_663397.1	RtcB	68..505	CDD:376465	383/436 (88%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167849755
Domainoid	1	1.000	784	1.000	Domainoid score	I78
eggNOG	1	0.900	-	-		E1_COG1690
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H36344
Inparanoid	1	1.050	881	1.000	Inparanoid score	I403
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60604
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004814
OrthoInspector	1	1.000	-	-		oto94170
orthoMCL	1	0.900	-	-		OOG6_101445
Panther	1	1.100	-	-	LDO	PTHR11118
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2780
SonicParanoid	1	1.000	-	-		X3956
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.790