Protein Alignment RtcB and rtcb-1

DIOPT Version :9

• Sequence 1: NP_609965.1
• Gene: RtcB / 35220
• FlyBaseID: FBgn0032781
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_492498.1
• Gene: rtcb-1 / 184556
• WormBaseID: WBGene00008877
• Length: 505
• Species: Caenorhabditis elegans
• Alignment Length: 503
• Identity: 377/503 - (74%)
• Similarity: 438/503 - (87%)
• Gaps: 0/503 - (0%)

  Fly     4 RPYNDELRYLEKVSDHCWRIKKGFQPNMNVEGCFYVNSRLERLMLEELKNSCRPGAVGGFLPGVK 68
            |.:.:|..::::::|..:||||||.|||||||.||||:.||:||.:|||.||....:|||||.|:
 Worm     3 RTFEEECDFIDRLTDTKFRIKKGFVPNMNVEGRFYVNNSLEQLMFDELKFSCDGQGIGGFLPAVR 67

  Fly    69 QIANVAALPGIVGRSIGLPDIHSGYGFAIGNMAAFDMNDPLSVVSPGGVGFDINCGVRLLRTNLY 133
            ||||||:||||||.|||||||||||||:|||:||||:.:|.||:||||||||||||||||||||:
 Worm    68 QIANVASLPGIVGHSIGLPDIHSGYGFSIGNIAAFDVGNPESVISPGGVGFDINCGVRLLRTNLF 132

  Fly   134 EKDVQPVKEQLAQSLFDHIPVGVGSKGIIPMNARDLEEALEMGMDWSLREGYVWAEDKEHCEEYG 198
            |::|:|:||||.|||||||||||||:|.|||.|.||.|.|||||||:|||||.||||||||||||
 Worm   133 EENVKPLKEQLTQSLFDHIPVGVGSRGAIPMLASDLVECLEMGMDWTLREGYSWAEDKEHCEEYG 197

  Fly   199 RMLNADPAKVSMRAKKRGLPQLGTLGAGNHYAEIQVVDEIYDKWSASKMGIEEKGQVVVMIHSGS 263
            |||.||.:|||:|||||||||||||||||||||:|||||||||.:||.|||:|:||||||:|.||
 Worm   198 RMLQADASKVSLRAKKRGLPQLGTLGAGNHYAEVQVVDEIYDKHAASTMGIDEEGQVVVMLHCGS 262

  Fly   264 RGFGHQVATDALVQMEKAMKRDKIETNDRQLACARINSVEGQDYLKAMAAAANFAWVNRSSMTFL 328
            ||.|||||||:||:|||||.||.|..||:||||||||||||::|...|||||||||||||.:||.
 Worm   263 RGLGHQVATDSLVEMEKAMARDGIVVNDKQLACARINSVEGKNYFSGMAAAANFAWVNRSCITFC 327

  Fly   329 TRQAFAKMFNTTPDDLDMHVIYDVSHNIAKVENHMVDGKERKLLVHRKGSTRAFPPHHPLIPVDY 393
            .|.||.|.|..:.||:||.||||||||:||:|.|||||:.|:|.|||||:|||||.|||||||||
 Worm   328 VRNAFQKTFGMSADDMDMQVIYDVSHNVAKMEEHMVDGRPRQLCVHRKGATRAFPAHHPLIPVDY 392

  Fly   394 QLTGQPVLVGGTMGTCSYVLTGTEQGMQETFGSTCHGAGRALSRAKSRRNLDYKDVLDKLDQLGI 458
            ||.|||||:||:||||||||||||||:.||||:||||||||||||||||.:.:..|:|.|.:..|
 Worm   393 QLIGQPVLIGGSMGTCSYVLTGTEQGLVETFGTTCHGAGRALSRAKSRRTITWDSVIDDLKKKEI 457

  Fly   459 AIRVASPKLVMEEAPESYKDVTDVVDTCHAAGISKKCIKMRPIAVIKG 506
            :||:|||||:|||||||||:||||||||.|||||||.:|:||||||||
 Worm   458 SIRIASPKLIMEEAPESYKNVTDVVDTCDAAGISKKAVKLRPIAVIKG 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RtcB	NP_609965.1	RtcB	67..506	CDD:224604	341/438 (78%)
		RtcB	67..506	CDD:279481	341/438 (78%)
rtcb-1	NP_492498.1	RtcB	28..505	CDD:224604	366/476 (77%)
		RtcB	65..505	CDD:279481	341/439 (78%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167003
Domainoid	1	1.000	708	1.000	Domainoid score	I49
eggNOG	1	0.900	-	-		E1_COG1690
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H36344
Inparanoid	1	1.050	775	1.000	Inparanoid score	I268
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60604
OrthoDB	1	1.010	-	-		D203128at33208
OrthoFinder	1	1.000	-	-		FOG0004814
OrthoInspector	1	1.000	-	-		oto20184
orthoMCL	1	0.900	-	-		OOG6_101445
Panther	1	1.100	-	-	LDO	PTHR11118
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2780
SonicParanoid	1	1.000	-	-		X3956
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.800