Protein Alignment Alp12 and PHO8

DIOPT Version :9

• Sequence 1: NP_001188848.1
• Gene: Alp12 / 35218
• FlyBaseID: FBgn0032779
• Length: 596
• Species: Drosophila melanogaster
• Sequence 2: NP_010769.3
• Gene: PHO8 / 852092
• SGDID: S000002889
• Length: 566
• Species: Saccharomyces cerevisiae
• Alignment Length: 613
• Identity: 159/613 - (25%)
• Similarity: 249/613 - (40%)
• Gaps: 155/613 - (25%)

  Fly    46 GNDQSN-PVQHTKWFRSRLFLISVVFSALLITAMCIGFVVHYGMSGDVGDMETVSYWPVDLPKEQ 109
            |:|.|: |.:.....||::.:.:||...||:..:.:.|...:.:
Yeast    16 GSDSSSRPKKRRISKRSKIIVSTVVCIGLLLVLVQLAFPSSFAL--------------------- 59

  Fly   110 KEWYDQGIDELQKAVSRQFNRRRAKNVILFVGDGMGPNTVTAARILGVK------EEGLLRWEQF 168
                        ::.|     .:.||||.||.|||||.:::.||.....      ::.|...|.|
Yeast    60 ------------RSAS-----HKKKNVIFFVTDGMGPASLSMARSFNQHVNDLPIDDILTLDEHF 107

  Fly   169 PDMGLLKTYCADKQVPDSFSTATALFGGVKVNYETGGVDANVPLGNCSASLKEDHH--VQTILKW 231
              :|..:|..:|..|.||.:.|||....:|......|||              .||  ..|:|:.
Yeast   108 --IGSSRTRSSDSLVTDSAAGATAFACALKSYNGAIGVD--------------PHHRPCGTVLEA 156

  Fly   232 AQVDGMRTGFVTTTRVTHATPAALYAHVPDRRWECESGMPAEAQGQGCMDIARQLIEQPTGQSIN 296
            |::.|..||.|.|||:|.||||:..:|| |.||            |..:....||.|.|.|:.::
Yeast   157 AKLAGYLTGLVVTTRITDATPASFSSHV-DYRW------------QEDLIATHQLGEYPLGRVVD 208

  Fly   297 VIMGGGRQMLVSDVTGSAADPLDTWAGQSKDGRDLIRDWRLKKADEGVSHAVV-----QNNRELW 356
            ::|||||......  |..|.|.. ..|..|||||||        ||..|:...     :|...|.
Yeast   209 LLMGGGRSHFYPQ--GEKASPYG-HHGARKDGRDLI--------DEAQSNGWQYVGDRKNFDSLL 262

  Fly   357 NLNGQDVDY-VLGIFANGHLMYDHERDRSDAGMPSLS---NMTLKALEVLGNSDK---GFLLVVE 414
            ..:|::|.. .||:||:..:.::.:||..:  .|||.   .:.|.|||...|.||   ||.|:||
Yeast   263 KSHGENVTLPFLGLFADNDIPFEIDRDEKE--YPSLKEQVKVALGALEKASNEDKDSNGFFLMVE 325

  Fly   415 AGLIDQAHHRGNARKALSEVLELNAAVESTLSFLKSSDRLDETLVIVTADHSHSLTINGHPDRGS 479
            ...||.|.|:.:....:.|||..:.|.:..|.|.::||  .||:::.|:||.....:.......|
Yeast   326 GSRIDHAGHQNDPASQVREVLAFDEAFQYVLEFAENSD--TETVLVSTSDHETGGLVTSRQVTAS 388

  Fly   480 --------SILGLAGNSKTEGTPYTTLTYGTSYQGFQVDPQTQSRKDPTADDITAWEYTQ---QA 533
                    .:|..|.:| .|......:.:...::|.....:...:.:....|:..::||.   :.
Yeast   389 YPQYVWYPQVLANATHS-GEFLKRKLVDFVHEHKGASSKIENFIKHEILEKDLGIYDYTDSDLET 452

  Fly   534 AINTDEN---------------------LHGGS--DVTIHA----DGAMSYLFH---GVHEQSYV 568
            .|:.|:|                     .||.|  ||.|:|    ....||:.:   |.||.:
Yeast   453 LIHLDDNANAIQDKLNDMVSFRAQIGWTTHGHSAVDVNIYAYANKKATWSYVLNNLQGNHENT-- 515

  Fly   569 AHAISYALRIGRFRDSSIAETLAELTPI 596
                    .:|:|.::.:...|.|:|.:
Yeast   516 --------EVGQFLENFLELNLNEVTDL 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Alp12	NP_001188848.1	ALP_like	134..579	CDD:304875	142/505 (28%)
PHO8	NP_010769.3	PhoA	8..530	CDD:224699	156/606 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345747
Domainoid	1	1.000	140	1.000	Domainoid score	I1026
eggNOG	1	0.900	-	-		E1_COG1785
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	141	1.000	Inparanoid score	I1177
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000192
OrthoInspector	1	1.000	-	-		otm46490
orthoMCL	1	0.900	-	-		OOG6_100381
Panther	1	1.100	-	-	O	PTHR11596
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R959
SonicParanoid	1	1.000	-	-		X159
TreeFam	0	0.000	Not matched by this tool.
	12	11.820