Protein Alignment Alp12 and alpi.2

DIOPT Version :9

• Sequence 1: NP_001188848.1
• Gene: Alp12 / 35218
• FlyBaseID: FBgn0032779
• Length: 596
• Species: Drosophila melanogaster
• Sequence 2: NP_001020359.1
• Gene: alpi.2 / 574009
• ZFINID: ZDB-GENE-050626-142
• Length: 521
• Species: Danio rerio
• Alignment Length: 504
• Identity: 199/504 - (39%)
• Similarity: 281/504 - (55%)
• Gaps: 49/504 - (9%)

  Fly   105 LPKEQKE---WYDQGIDELQKAVSRQFNRRRAKNVILFVGDGMGPNTVTAARIL------GVKEE 160
            :|:|:|.   ||.:..|.|..::|..||..||||:|||:|||||.:||||||:|      ...||
Zfish    25 VPEEEKNPNFWYVKAKDSLHASLSMTFNTHRAKNLILFLGDGMGISTVTAARVLKGQMNKKTGEE 89

  Fly   161 GLLRWEQFPDMGLLKTYCADKQVPDSFSTATALFGGVKVNYETGGVDANVPLGNCSASLKEDHHV 225
            .:|..:.||.:.|.|||..|:|:|||.:||||...|||.||.|.|:.|......|| |:| .:.|
Zfish    90 SVLAMDTFPYLALSKTYNVDQQMPDSAATATAYLCGVKANYGTLGLSAAAQREVCS-SVK-GNEV 152

  Fly   226 QTILKWAQVDGMRTGFVTTTRVTHATPAALYAHVPDRRWECESGMPAEAQGQGCMDIARQLIEQP 290
            ::||..|::.|...|.|:|.||.||:|||.|:|.|:|.|..:..:.:||...||.|||.|||
Zfish   153 KSILHQAKMAGKSVGIVSTARVQHASPAASYSHTPERGWYSDKELTSEAVAGGCQDIAVQLI--- 214

  Fly   291 TGQSINVIMGGGRQMLVSDVTGSAADP-LDTWAGQSKDGRDLIRDWRLKKADEGVSHAVVQNNRE 354
            |...||||:|||||.:....|   .|| ..|..|..||.|:|:.:| ||..         :|.:.
Zfish   215 TNTDINVILGGGRQYMFPRET---TDPEYSTVTGSRKDKRNLVDEW-LKNR---------KNAQY 266

  Fly   355 LWN------LNGQDVDYVLGIFANGHLMYDHERD-RSDAGMPSLSNMTLKALEVLGNSDKGFLLV 412
            :||      :|....||::|:|......|:.||| :.|   |||:.|..||:::|..:..||.|.
Zfish   267 VWNKQQFDAVNEDKTDYLMGLFEPKDTRYELERDPKMD---PSLTEMVEKAIKILRKNPNGFYLF 328

  Fly   413 VEAGLIDQAHHRGNARKALSEVLELNAAVESTLSFLKSSDRLDETLVIVTADHSHSLTINGHPDR 477
            ||.|.||..||.|.|:.||:|.:|.:.::|.........|    ||.:|||||||..:..|:..|
Zfish   329 VEGGRIDHGHHAGQAKYALTEAVEFDNSIERAGQLTSELD----TLSVVTADHSHVFSFGGYSYR 389

  Fly   478 GSSILGLAGNSKTEGTPYTTLTYGTSYQGFQVDPQTQSRKDPTADDITAW--EYTQQAAINTDEN 540
            |:.:||::.....:|..:|...||.. .|:|:...|:    |..::..:.  :|.||||:..|..
Zfish   390 GNPVLGVSYAKGEDGKSFTNALYGNG-PGYQITNGTR----PDVNESVSGRDDYLQQAAVPLDSE 449

  Fly   541 LHGGSDVTIHADGAMSYLFHGVHEQSYVAHAISYALRIGRFRDSSIAET 589
            .||..||.|.|.|.|::|||||.||||:.||:::|..|..:.|..:.::
Zfish   450 THGSEDVAIFAKGPMAHLFHGVQEQSYIPHAMAFAACIEPYSDCQLHDS 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Alp12	NP_001188848.1	ALP_like	134..579	CDD:304875	185/460 (40%)
alpi.2	NP_001020359.1	Alk_phosphatase	56..487	CDD:278666	186/460 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593243
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48882
OrthoDB	1	1.010	-	-		D216917at33208
OrthoFinder	1	1.000	-	-		FOG0000192
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100381
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X159
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.760