Protein Alignment Alp12 and alpi.1

DIOPT Version :9

• Sequence 1: NP_001188848.1
• Gene: Alp12 / 35218
• FlyBaseID: FBgn0032779
• Length: 596
• Species: Drosophila melanogaster
• Sequence 2: NP_001014375.1
• Gene: alpi.1 / 541539
• ZFINID: ZDB-GENE-050327-78
• Length: 532
• Species: Danio rerio
• Alignment Length: 518
• Identity: 201/518 - (38%)
• Similarity: 279/518 - (53%)
• Gaps: 56/518 - (10%)

  Fly    72 ALLITAMCIGFVVHYGMSGDVGDMETVSYWPVDLPKEQKEWYDQGIDELQKAVSRQFNRRRAKNV 136
            ||::...|              .:::.:.|    .|:...|.||....||.|::......||||:
Zfish    18 ALVLNTSC--------------SLDSAAEW----EKDPAYWNDQARRTLQTALTLPLRVNRAKNI 64

  Fly   137 ILFVGDGMGPNTVTAARILGVKEEG------LLRWEQFPDMGLLKTYCADKQVPDSFSTATALFG 195
            |||||||||.:||:|||||..:.||      :|..:.||.:.|.||||.||||.||.|||||...
Zfish    65 ILFVGDGMGVSTVSAARILRGQMEGQSGEETILAMDTFPYLALSKTYCVDKQVADSASTATAYHC 129

  Fly   196 GVKVNYETGGVDANVPLGNCSASLKEDHHVQTILKWAQVDGMRTGFVTTTRVTHATPAALYAHVP 260
            |||.|.:|.|:.|......|:.:.  .:.|.::|..|:..|...|.||||||.||:|||.|||..
Zfish   130 GVKANAKTVGLSAKAVAYECNTTF--GNEVFSVLHRAKAQGKSVGIVTTTRVQHASPAAAYAHSV 192

  Fly   261 DRRWECESGMPAEAQGQGCMDIARQLIEQPTGQSINVIMGGGRQMLVSDVTGSAADPLDTWAGQS 325
            .|:|..::.:|:||:.|||.|||.||:   |...|:||:||||..:....|........:..|..
Zfish   193 SRKWYSDADVPSEARRQGCKDIATQLV---TNTDIDVILGGGRMYMTPKGTPDPEYSSSSHKGDR 254

  Fly   326 KDGRDLIRDWRLKKADEGVSHAVVQNNRELWN---LNGQDV---DYVLGIFANGHLMYDHERDRS 384
            ||.::||..|  ..|.:|      :|.:.:||   .|..||   |.::|:|....:.::..|:|:
Zfish   255 KDKKNLINVW--LNARKG------RNAQYVWNKEQFNAVDVKTTDCLMGLFEPKDMRFEVFRNRT 311

  Fly   385 DAGMPSLSNMTLKALEVLGNSDKGFLLVVEAGLIDQAHHRGNARKALSEVLELNAAVESTLSFLK 449
            ..  ||:.:||.||:::|..:.|||.|.||.|.||..||.|.|:.||:|.:..:.|::.......
Zfish   312 RD--PSIVDMTEKAIQILSKNPKGFFLFVEGGRIDHGHHDGVAKLALTETIMFDRAIQRASELTS 374

  Fly   450 SSDRLDETLVIVTADHSHSLTINGHPDRGSSILGLAGNSKTEGTPYTTLTY--GTSYQGFQVDPQ 512
            .||    ||.:|||||||..|..|...||:.|.|||.....:..|||::.|  |..|     |..
Zfish   375 ESD----TLTVVTADHSHVFTFGGKTPRGNPIFGLAPKQAEDDLPYTSILYANGPGY-----DHV 430

  Fly   513 TQSRKDPTADDITAWEYTQQAAINTDENLHGGSDVTIHADGAMSYLFHGVHEQSYVAHAISYA 575
            ..:|.:.:..|....||.||||:..:...|||.||.|:|.|.|::|||||.||:|||||::||
Zfish   431 NGTRGNVSVLDYYDEEYKQQAAVPLESETHGGEDVAIYAKGPMAHLFHGVKEQNYVAHAMAYA 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Alp12	NP_001188848.1	ALP_like	134..579	CDD:304875	188/456 (41%)
alpi.1	NP_001014375.1	PhoA	46..493	CDD:224699	191/470 (41%)
		Alk_phosphatase	61..496	CDD:278666	189/457 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593230
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48882
OrthoDB	1	1.010	-	-		D216917at33208
OrthoFinder	1	1.000	-	-		FOG0000192
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100381
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X159
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.760