Protein Alignment Alp12 and alpi.1

DIOPT Version :10

• Sequence 1: NP_609963.1
• Gene: Alp12 / 35218
• FlyBaseID: FBgn0032779
• Length: 596
• Species: Drosophila melanogaster
• Sequence 2: NP_001014375.1
• Gene: alpi.1 / 541539
• ZFINID: ZDB-GENE-050327-78
• Length: 532
• Species: Danio rerio
• Alignment Length: 518
• Identity: 201/518 - (38%)
• Similarity: 279/518 - (53%)
• Gaps: 56/518 - (10%)

  Fly    72 ALLITAMCIGFVVHYGMSGDVGDMETVSYWPVDLPKEQKEWYDQGIDELQKAVSRQFNRRRAKNV 136
            ||::...|              .:::.:.|    .|:...|.||....||.|::......||||:
Zfish    18 ALVLNTSC--------------SLDSAAEW----EKDPAYWNDQARRTLQTALTLPLRVNRAKNI 64

  Fly   137 ILFVGDGMGPNTVTAARILGVKEEG------LLRWEQFPDMGLLKTYCADKQVPDSFSTATALFG 195
            |||||||||.:||:|||||..:.||      :|..:.||.:.|.||||.||||.||.|||||...
Zfish    65 ILFVGDGMGVSTVSAARILRGQMEGQSGEETILAMDTFPYLALSKTYCVDKQVADSASTATAYHC 129

  Fly   196 GVKVNYETGGVDANVPLGNCSASLKEDHHVQTILKWAQVDGMRTGFVTTTRVTHATPAALYAHVP 260
            |||.|.:|.|:.|......|:.:.  .:.|.::|..|:..|...|.||||||.||:|||.|||..
Zfish   130 GVKANAKTVGLSAKAVAYECNTTF--GNEVFSVLHRAKAQGKSVGIVTTTRVQHASPAAAYAHSV 192

  Fly   261 DRRWECESGMPAEAQGQGCMDIARQLIEQPTGQSINVIMGGGRQMLVSDVTGSAADPLDTWAGQS 325
            .|:|..::.:|:||:.|||.|||.||:   |...|:||:||||..:....|........:..|..
Zfish   193 SRKWYSDADVPSEARRQGCKDIATQLV---TNTDIDVILGGGRMYMTPKGTPDPEYSSSSHKGDR 254

  Fly   326 KDGRDLIRDWRLKKADEGVSHAVVQNNRELWN---LNGQDV---DYVLGIFANGHLMYDHERDRS 384
            ||.::||..|  ..|.:|      :|.:.:||   .|..||   |.::|:|....:.::..|:|:
Zfish   255 KDKKNLINVW--LNARKG------RNAQYVWNKEQFNAVDVKTTDCLMGLFEPKDMRFEVFRNRT 311

  Fly   385 DAGMPSLSNMTLKALEVLGNSDKGFLLVVEAGLIDQAHHRGNARKALSEVLELNAAVESTLSFLK 449
            ..  ||:.:||.||:::|..:.|||.|.||.|.||..||.|.|:.||:|.:..:.|::.......
Zfish   312 RD--PSIVDMTEKAIQILSKNPKGFFLFVEGGRIDHGHHDGVAKLALTETIMFDRAIQRASELTS 374

  Fly   450 SSDRLDETLVIVTADHSHSLTINGHPDRGSSILGLAGNSKTEGTPYTTLTY--GTSYQGFQVDPQ 512
            .||    ||.:|||||||..|..|...||:.|.|||.....:..|||::.|  |..|     |..
Zfish   375 ESD----TLTVVTADHSHVFTFGGKTPRGNPIFGLAPKQAEDDLPYTSILYANGPGY-----DHV 430

  Fly   513 TQSRKDPTADDITAWEYTQQAAINTDENLHGGSDVTIHADGAMSYLFHGVHEQSYVAHAISYA 575
            ..:|.:.:..|....||.||||:..:...|||.||.|:|.|.|::|||||.||:|||||::||
Zfish   431 NGTRGNVSVLDYYDEEYKQQAAVPLESETHGGEDVAIYAKGPMAHLFHGVKEQNYVAHAMAYA 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Alp12	NP_609963.1	ALP_like	134..579	CDD:474031	188/456 (41%)
alpi.1	NP_001014375.1	Alk_phosphatase	61..496	CDD:395188	189/457 (41%)