Protein Alignment Alp12 and Alpi

DIOPT Version :10

• Sequence 1: NP_609963.1
• Gene: Alp12 / 35218
• FlyBaseID: FBgn0032779
• Length: 596
• Species: Drosophila melanogaster
• Sequence 2: NP_073156.3
• Gene: Alpi / 24197
• RGDID: 2099
• Length: 540
• Species: Rattus norvegicus
• Alignment Length: 510
• Identity: 189/510 - (37%)
• Similarity: 265/510 - (51%)
• Gaps: 45/510 - (8%)

  Fly   105 LPKEQKE---WYDQGIDELQKAVSRQFNRRRAKNVILFVGDGMGPNTVTAARIL------GVKEE 160
            :|.|::.   |..:..:.|..|...|..:..|||:|||:|||||..||||.|||      .:..|
  Rat    22 IPVEEENPVFWNQKAKEALDVAKKLQPIQTSAKNLILFLGDGMGVPTVTATRILKGQLGGHLGPE 86

  Fly   161 GLLRWEQFPDMGLLKTYCADKQVPDSFSTATALFGGVKVNYETGGVDANVPLGNCSASLKEDHHV 225
            ..|..:.||...|.|||..|:|||||..||||...|||.||:|.||.|......|:::.  .:.|
  Rat    87 TPLAMDHFPFTALSKTYNVDRQVPDSAGTATAYLCGVKANYKTIGVSAAARFNQCNSTF--GNEV 149

  Fly   226 QTILKWAQVDGMRTGFVTTTRVTHATPAALYAHVPDRRWECESGMPAEAQGQGCMDIARQLIEQP 290
            .:::..|:..|...|.||||||.||:||..|||..:|.|..::.||:.|..:||.|||.|||
  Rat   150 FSVMHRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRDWYSDADMPSSALQEGCKDIATQLI--- 211

  Fly   291 TGQSINVIMGGGRQMLVSDVTGSAADPLDT-WAGQSKDGRDLIRDWRLKKADEGVSHAVVQNNRE 354
            :...|:||:||||:.:....|.....|.|: .:|...|.|:|:.:|..|          .|..|.
  Rat   212 SNMDIDVILGGGRKFMFPKGTPDPEYPGDSDQSGVRLDSRNLVEEWLAK----------YQGTRY 266

  Fly   355 LWNLN-----GQD--VDYVLGIFANGHLMYDHERDRSDAGMPSLSNMTLKALEVLGNSDKGFLLV 412
            :||..     .||  |..::|:|....:.||..|:.|  ..|||:.||..|:.:|..:.:||.|.
  Rat   267 VWNREQLMQASQDPAVTRLMGLFEPAEMKYDVNRNAS--ADPSLAEMTEVAVRLLSRNPQGFYLF 329

  Fly   413 VEAGLIDQAHHRGNARKALSEVLELNAAVESTLSFLKSSDRLDETLVIVTADHSHSLTINGHPDR 477
            ||.|.|||.||.|.|..||:|.:..::|:|.........|    ||.::||||||.....|:..|
  Rat   330 VEGGRIDQGHHAGTAYLALTEAVMFDSAIEKASQLTNEKD----TLTLITADHSHVFAFGGYTLR 390

  Fly   478 GSSILGLAGNSKTEGTPYTTLTYGTSYQGFQVDPQTQSRKDPTADDITAWE--YTQQAAINTDEN 540
            |:||.|||..:..:|..||::.||.. .|:.::    |...|...|..:.:  |.||||:.....
  Rat   391 GTSIFGLAPLNAQDGKSYTSILYGNG-PGYVLN----SGNRPNVTDAESGDVNYKQQAAVPLSSE 450

  Fly   541 LHGGSDVTIHADGAMSYLFHGVHEQSYVAHAISYALRIGRFRDSSIAETLAELTP 595
            .|||.||.|.|.|..::|.|||.||:|:||.:::|..:..:.|..:|....|..|
  Rat   451 THGGEDVAIFARGPQAHLVHGVQEQNYIAHVMAFAGCLEPYTDCGLAPPADENRP 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Alp12	NP_609963.1	ALP_like	134..579	CDD:474031	178/460 (39%)
Alpi	NP_073156.3	Alk_phosphatase	53..488	CDD:395188	179/460 (39%)