Protein Alignment Alp12 and Alpl

DIOPT Version :10

• Sequence 1: NP_609963.1
• Gene: Alp12 / 35218
• FlyBaseID: FBgn0032779
• Length: 596
• Species: Drosophila melanogaster
• Sequence 2: NP_031457.2
• Gene: Alpl / 11647
• MGIID: 87983
• Length: 524
• Species: Mus musculus
• Alignment Length: 498
• Identity: 208/498 - (41%)
• Similarity: 277/498 - (55%)
• Gaps: 26/498 - (5%)

  Fly    92 VGDMETVSYWPVDLPKEQKEWYDQGIDELQKAVSRQ-FNRRRAKNVILFVGDGMGPNTVTAARIL 155
            :|...|.|:.| :..::...|..|..:.|:.|:..| .|...|||||:|:|||||.:||||||||
Mouse    10 IGTCLTNSFVP-EKERDPSYWRQQAQETLKNALKLQKLNTNVAKNVIMFLGDGMGVSTVTAARIL 73

  Fly   156 ------GVKEEGLLRWEQFPDMGLLKTYCADKQVPDSFSTATALFGGVKVNYETGGVDANVPLGN 214
                  ...||..|..::||.:.|.|||..:.|||||..||||...|||.|..|.||.|......
Mouse    74 KGQLHHNTGEETRLEMDKFPFVALSKTYNTNAQVPDSAGTATAYLCGVKANEGTVGVSAATERTR 138

  Fly   215 CSASLKEDHHVQTILKWAQVDGMRTGFVTTTRVTHATPAALYAHVPDRRWECESGMPAEAQGQGC 279
            |:.:  :.:.|.:||:||:..|...|.||||||.||||:|.|||..||.|..::.||.||..|||
Mouse   139 CNTT--QGNEVTSILRWAKDAGKSVGIVTTTRVNHATPSAAYAHSADRDWYSDNEMPPEALSQGC 201

  Fly   280 MDIARQLIEQPTGQSINVIMGGGRQMLVSDVTGSAADPLDTWA-GQSKDGRDLIRDWRLKKADEG 343
            .|||.||:...  :.|:|||||||:.:...........||..| |...||.|||..|:..|....
Mouse   202 KDIAYQLMHNI--KDIDVIMGGGRKYMYPKNRTDVEYELDEKARGTRLDGLDLISIWKSFKPRHK 264

  Fly   344 VSHAVVQNNRELWNLNGQDVDYVLGIFANGHLMYDHERDRSDAGMPSLSNMTLKALEVLGNSDKG 408
            .|| .|.|..||..|:...|||:||:|..|.:.|  |.:|::...||||.|...||.:|..:.||
Mouse   265 HSH-YVWNRTELLALDPSRVDYLLGLFEPGDMQY--ELNRNNLTDPSLSEMVEVALRILTKNLKG 326

  Fly   409 FLLVVEAGLIDQAHHRGNARKALSEVLELNAAVESTLSFLKSSDRLDETLVIVTADHSHSLTING 473
            |.|:||.|.||..||.|.|::||.|.:|::.|:....:.....|    ||.:|||||||..|..|
Mouse   327 FFLLVEGGRIDHGHHEGKAKQALHEAVEMDQAIGKAGAMTSQKD----TLTVVTADHSHVFTFGG 387

  Fly   474 HPDRGSSILGLAGN-SKTEGTPYTTLTYGTSYQGFQ-VDPQTQSRKDPTADDITAWEYTQQAAIN 536
            :..||:||.|||.. |.|:..|:|.:.||.. .|:: ||.:   |::.:..|.....|..|:|:.
Mouse   388 YTPRGNSIFGLAPMVSDTDKKPFTAILYGNG-PGYKVVDGE---RENVSMVDYAHNNYQAQSAVP 448

  Fly   537 TDENLHGGSDVTIHADGAMSYLFHGVHEQSYVAHAISYALRIG 579
            .....|||.||.:.|.|.|::|.||||||:|:.|.::||..||
Mouse   449 LRHETHGGEDVAVFAKGPMAHLLHGVHEQNYIPHVMAYASCIG 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Alp12	NP_609963.1	ALP_like	134..579	CDD:474031	195/453 (43%)
Alpl	NP_031457.2	Alk_phosphatase	51..490	CDD:395188	196/453 (43%)