Protein Alignment Alp12 and Alpp

DIOPT Version :10

• Sequence 1: NP_609963.1
• Gene: Alp12 / 35218
• FlyBaseID: FBgn0032779
• Length: 596
• Species: Drosophila melanogaster
• Sequence 2: XP_002730104.3
• Gene: Alpp / 100359675
• RGDID: 2325055
• Length: 529
• Species: Rattus norvegicus
• Alignment Length: 503
• Identity: 181/503 - (35%)
• Similarity: 269/503 - (53%)
• Gaps: 47/503 - (9%)

  Fly   105 LPKEQKE---WYDQGIDELQKAVSRQFNRRRAKNVILFVGDGMGPNTVTAARILGVKEEG----- 161
            :|.|::.   |..:..:.|:.|...|..:..|.|:|:.:|||||.:||||.|||..:::|
  Rat    20 VPVEEENPAFWNRKAAEALEAAKKLQPIQTSANNLIILMGDGMGVSTVTATRILKGQQQGHLGPE 84

  Fly   162 -LLRWEQFPDMGLLKTYCADKQVPDSFSTATALFGGVKVNYETGGVDANVPLGNCSASLKEDHHV 225
             .|..::||.|.|.|||..|||||||..|.||...|||.|.:..|:.|......|:.:.  .:.|
  Rat    85 TPLAMDRFPHMALSKTYNTDKQVPDSAGTGTAFLCGVKTNMKVIGLSAAARFNQCNTTW--GNEV 147

  Fly   226 QTILKWAQVDGMRTGFVTTTRVTHATPAALYAHVPDRRWECESGMPAEAQGQGCMDIARQLIEQP 290
            .:::..|:..|...|.||||.|.||:||..|||..:|.|..::.|...|..:||.|||.|||
  Rat   148 VSVMHRAKKAGKSVGVVTTTSVQHASPAGTYAHTVNRNWYSDAHMSTAALQEGCKDIAMQLI--- 209

  Fly   291 TGQSINVIMGGGRQMLVSDVTGSAADPLD-TWAGQSKDGRDLIRDWRLKKADEGVSHAVVQNNRE 354
            :...|:||:||||:.:....|.....|.| ..||...|||:|:::|..|  .:|..:  |.|..|
  Rat   210 SNTDIDVILGGGRKFMFPKGTPDQEYPTDPQQAGTRLDGRNLVQEWLAK--HQGAQY--VWNRTE 270

  Fly   355 L--WNLNGQDVDYVLGIFANGHLMYDHERDRSDAGMPSLSNMTLKALEVLGNSDKGFLLVVEAGL 417
            |  .:|| :.|.:::|:|....:.|:.:||.:..  |||:.||..|:.:|..:.|||.|.||.|.
  Rat   271 LIQASLN-RSVTHLMGLFEPNDMKYNIDRDPTQD--PSLAEMTEVAVHMLSRNPKGFYLFVEGGR 332

  Fly   418 IDQAHHRGNARKALSEVLELNAAVESTLSFLKSSDRL---DETLVIVTADHSHSLTINGHPDRGS 479
            ||..||...|.:||:|.:..::||:       .:|:|   .:|::||||||||..:..|:..|.:
  Rat   333 IDHGHHEAIAYRALTEAVMFDSAVD-------KADKLTSEKDTMIIVTADHSHVFSFGGYTQREA 390

  Fly   480 SILGLAGNSKTEGTPYTTLTYGT--SYQ---GFQVDPQTQSRKDPTADDITAWEYTQQAAINTDE 539
            ||.|||.....:|..:|::.||.  .|:   |.:.|...:...:||        |.||||:....
  Rat   391 SIFGLAPFKAGDGKSFTSILYGNGPGYKLNNGIRADVTEEESSNPT--------YQQQAAVPLSS 447

  Fly   540 NLHGGSDVTIHADGAMSYLFHGVHEQSYVAHAISYALRIGRFRDSSIA 587
            ..|.|.||.|.|.|..::|.|||.||:|:||.:::|..:..:.|..:|
  Rat   448 ETHSGEDVAIFARGPQAHLVHGVQEQNYIAHVMAFAGCLEPYTDCGLA 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Alp12	NP_609963.1	ALP_like	134..579	CDD:474031	172/461 (37%)
Alpp	XP_002730104.3	Alk_phosphatase	51..486	CDD:395188	173/461 (38%)