DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lectin-galC1 and CLEC4M

DIOPT Version :9

Sequence 1:	NP_001188845.1	Gene:	Lectin-galC1 / 35216	FlyBaseID:	FBgn0016675	Length:	186	Species:	Drosophila melanogaster
Sequence 2:	NP_055072.3	Gene:	CLEC4M / 10332	HGNCID:	13523	Length:	399	Species:	Homo sapiens

Alignment Length:	133	Identity:	34/133 - (25%)
Similarity:	59/133 - (44%)	Gaps:	28/133 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 YFFGTESLNWYEAYEKCRELNSELVTFETDQEFDAVTAFL---TANGSRLTYWTSGNDLAKTGSH 112
            ||......||:::...|:|:.::||..:|.:|.:    ||   |:..:|.: |...:||.:.|:.
Human   280 YFMSNSQRNWHDSVTACQEVRAQLVVIKTAEEQN----FLQLQTSRSNRFS-WMGLSDLNQEGTW 339

  Fly   113 RWFTNAQRISSLR--WARNQPDNAGQKEHCIHL---GYIYKDSRKFELNDRPCSQDPNSLFKYIC 172
            :|...:....|.:  |...:|:|:| .|.|...   |:          ||..|..|.    .:||
Human   340 QWVDGSPLSPSFQRYWNSGEPNNSG-NEDCAEFSGSGW----------NDNRCDVDN----YWIC 389

  Fly   173 EAP 175
            :.|
Human   390 KKP 392

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lectin-galC1	NP_001188845.1	CLECT	51..173	CDD:153057	32/129 (25%)
CLEC4M	NP_055072.3	Endocytosis signal. /evidence=ECO:0000250	14..15
		transmembrane domain	44..71
		7 X approximate tandem repeats	108..269
		DUF342	<140..251	CDD:302792
		CLECT_DC-SIGN_like	268..391	CDD:153060	33/130 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1509611at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22802
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.020