Protein Alignment Pax and Ajuba

DIOPT Version :9

• Sequence 1: NP_001033913.1
• Gene: Pax / 35215
• FlyBaseID: FBgn0041789
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: NP_445955.1
• Gene: Ajuba / 85265
• RGDID: 620407
• Length: 548
• Species: Rattus norvegicus
• Alignment Length: 570
• Identity: 131/570 - (22%)
• Similarity: 194/570 - (34%)
• Gaps: 177/570 - (31%)

  Fly    37 NSVPG-QPQQPQPQYGTVQPKHQA---LQQQQFVDNTPGYGSLRGKAQPQVYQE--HYSVETRSP 95
            |..|| :..:|..:.|.:..:..|   .:.|:|..:.|| |....:|.|.....  .:.:||.:|
  Rat    63 NGGPGDEALEPAREQGPLDAERNARGSFEAQRFEGSFPG-GPPPTRALPLPLSSPPDFRLETTAP 126

  Fly    96 TAGHDFNGSSTTPGYANQGSLPR-----QAAGAS------------TGLS-----------ELDS 132
            ......:.:|::...|::.|.||     ..||||            :|:|           ....
  Rat   127 ALSPRSSFASSSASDASKPSSPRGSLLLDGAGASGAGGSRPCSNRTSGISMGYDQRHGSPLPAGP 191

  Fly   133 LLQDLQKIDVPVNYSTPVSKYNTMNSYATVEERPSVDSLLKELDNAHIYAVPNGSAHKSPTPGRH 197
            .|..|.....|..||:.    ...::|      |.:.:.|..|           .||:
  Rat   192 CLFGLPLTTAPSGYSSG----GVPSAY------PELHAALDRL-----------CAHR------- 228

  Fly   198 VTITVRETKTEKLTGPDGPVGTVEEQIVQQKDSYTPNHAVPGQQVHQAYTSQATKELDDLMASLS 262
                              |||.   ...:.:.||.|....||     |.|....
  Rat   229 ------------------PVGF---GCQESRHSYPPALGSPG-----ALTGAVV----------- 256

  Fly   263 DFKVSNGTNG--IGNGSHPQQHSSTVQHQTVTDYARPNKGSQ-QAHLTQTIEETTIVEDSRE--- 321
                  ||.|  ...|:.|.:||       ||.|.....|:: |..||..: ..|:....||
  Rat   257 ------GTAGPLERRGTQPGRHS-------VTGYGDCAAGARYQDELTALL-RLTVATGGREAGA 307

  Fly   322 ---------DQLDSMLGNLQANMSRQGVNTVQK-----GCCNACEKPIVGQ--VITALGKTWHPE 370
                     ..|:...|:.....||..:...:.     |.|..|.|.|.||  ...||...:|.:
  Rat   308 RGEPLGIEPSGLEESPGSFVPEASRSRIREPEAREDYFGTCIKCNKGIYGQSNACQALDSLYHTQ 372

  Fly   371 HFTCNHCSQELGTRNFFERDGFPYCEPDYHNLFS------PRCAYCNGAILDKCVTALDKTWHTE 429
            .|.|..|.:.|..:.|:..:|..|||.||  |||      .:|..|...||:|.:.|:.|::|..
  Rat   373 CFVCCSCGRTLRCKAFYSVNGSVYCEEDY--LFSGFQEAAEKCCVCGHLILEKILQAMGKSYHPG 435

  Fly   430 HFFCAQCGQQFGEEGFHERDGKP---------YCRNDYFEMFAPKCNGCNRAIMEN-------YI 478
            .|.|..|.:..        ||.|         ||..||.:.:||||..|.:.|:.:       .:
  Rat   436 CFRCIVCNKCL--------DGVPFTVDFSNQVYCVTDYHKNYAPKCAACGQPILPSEGCEDIVRV 492

  Fly   479 SALNSQWHPDCFVCRDCRQPFQGGSFFDHEGLPYCETHYHAKRGSLCAGC 528
            .:::..:|.:|:.|.|||....     |.||........|.    ||.||
  Rat   493 ISMDRDYHFECYHCEDCRMQLS-----DEEGCCCFPLDGHL----LCHGC 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pax	NP_001033913.1	LIM1_Paxillin_like	348..400	CDD:259830	19/53 (36%)
		LIM2_Paxillin_like	407..458	CDD:188723	16/59 (27%)
		LIM3_Paxillin_like	466..518	CDD:188724	12/58 (21%)
		LIM4_Paxillin	525..576	CDD:188795	3/4 (75%)
Ajuba	NP_445955.1	PreLIM	1..345		69/361 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..182		27/119 (23%)
		Nuclear localization signal. /evidence=ECO:0000255	290..298		2/8 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	307..333		3/25 (12%)
		LIM1_Ajuba_like	348..401	CDD:188738	18/52 (35%)
		LIM2_Ajuba_like	413..465	CDD:188741	16/59 (27%)
		LIM3_Ajuba_like	473..534	CDD:188822	17/70 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910