DRSC/TRiP Functional Genomics Resources

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Protein Alignment Pax and LRG1

DIOPT Version :9

Sequence 1:NP_001033913.1 Gene:Pax / 35215 FlyBaseID:FBgn0041789 Length:581 Species:Drosophila melanogaster
Sequence 2:NP_010041.2 Gene:LRG1 / 851358 SGDID:S000002399 Length:1017 Species:Saccharomyces cerevisiae


Alignment Length:193 Identity:50/193 - (25%)
Similarity:75/193 - (38%) Gaps:42/193 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   331 LQANMSRQGVNTV---------QKGCCNACEKPIVGQ------VITALGKTWHPEHFTCNHCSQE 380
            :|.:...:.:||.         ||..|..|.|.::..      .:.||||.:|...|||..|.:.
Yeast     2 IQNSAGYRSLNTASPMTVQVKNQKKICARCNKLVIPDSQRTKTTLKALGKYYHESCFTCQDCQKP 66

  Fly   381 LGTRNFFERDGFPY-----------CEPDY---HNLFSPRCAYCNGAILDKCVTALDKTWHTEHF 431
            |..:.      |||           |:.||   |||.   |..|:..:.....||....:..|||
Yeast    67 LKPKY------FPYQVDKTSESILLCQYDYFRRHNLL---CHVCDTPLRGLYYTAFGYRYDEEHF 122

  Fly   432 FCAQCGQQFGEEGFHERDGKPYCRNDYFEMFAPKCNGCNRAIMENYISALNSQ----WHPDCF 490
            .|..|....|.:.......:.||:..:.:.|:.:|.||...|.:.||.....:    |||:|:
Yeast   123 SCTICATPCGVKKCFMYGNQLYCKYHFLKYFSKRCKGCEFPISDQYIEFPKGEEIHCWHPECY 185

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PaxNP_001033913.1 LIM1_Paxillin_like 348..400 CDD:259830 19/71 (27%)
LIM2_Paxillin_like 407..458 CDD:188723 12/50 (24%)
LIM3_Paxillin_like 466..518 CDD:188724 10/29 (34%)
LIM4_Paxillin 525..576 CDD:188795
LRG1NP_010041.2 LIM1_Lrg1p_like 28..90 CDD:188777 17/67 (25%)
LIM 98..149 CDD:259829 12/50 (24%)
LIM3_Lrg1p_like 419..475 CDD:188779
RhoGAP_fLRG1 728..959 CDD:239862
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1703
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 1 0.950 - 0 Normalized mean entropy S2376
OMA 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000055
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R1093
SonicParanoid 1 1.000 - - X39
TreeFam 00.000 Not matched by this tool.
54.880

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