DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pax and micall2

DIOPT Version :9

Sequence 1:	NP_001033913.1	Gene:	Pax / 35215	FlyBaseID:	FBgn0041789	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	NP_001072513.1	Gene:	micall2 / 779968	XenbaseID:	XB-GENE-979747	Length:	1023	Species:	Xenopus tropicalis

Alignment Length:	256	Identity:	61/256 - (23%)
Similarity:	102/256 - (39%)	Gaps:	52/256 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    94 SPTAGHDFNGSSTTPGYANQGSLPRQAAGASTGLSELDSLLQDLQKIDVPVNYS---TPVSKYNT 155
            ||..|   ||||||..|.:: |.|.|.|...:....:.:  .::.|.:.|.|:.   .|::|  |
Frog   657 SPITG---NGSSTTKSYLSK-SGPGQRAEEISSKGPVPN--SNVSKQETPENWRQNLKPIAK--T 713

  Fly   156 MNSYATVEERPSVDSLLKELDNAHIYAVPNGSAHKSPTPGRHVTITV----RETK-TEKLTGPDG 215
            ..:...|:  |.|..|.|:::||   |....|..|:||....|..|:    :|.| :|.||.|
Frog   714 PQTPGVVQ--PKVYPLPKDVENA---AKTTPSPQKTPTIINSVKTTLNFPGKENKPSECLTPP-- 771

  Fly   216 PVGTVEEQIVQQKDSYTPNHAVPGQQVHQAYTSQATKELDDLMASLSDFKVSNGTNGIGNGSHPQ 280
                    ..:.|:....:...|.::...........:....:....|..:.:.|      ..|.
Frog   772 --------AAKSKEDKASSSPTPPRKKLLPVNLDLINDWPKPVQKWQDVSLKDDT------KRPA 822

  Fly   281 QHSSTVQHQTVTDYARPNKGSQQAHLTQTIE-ETTIVEDSREDQLDSMLGNLQANMSRQGV 340
            .||| |..::..|.:| ||...:....:.|: :..|:    |.:||:        :.:|||
Frog   823 AHSS-VNERSKNDASR-NKARPEYIPKEEIQRQLQII----EQELDA--------LEQQGV 869

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pax	NP_001033913.1	LIM1_Paxillin_like	348..400	CDD:259830
		LIM2_Paxillin_like	407..458	CDD:188723
		LIM3_Paxillin_like	466..518	CDD:188724
		LIM4_Paxillin	525..576	CDD:188795
micall2	NP_001072513.1	CH	5..102	CDD:278723
		LIM_Mical_like_1	188..242	CDD:188828
		CytochromB561_N	513..>763	CDD:286826	35/118 (30%)
		Epiglycanin_TR	601..666	CDD:283334	6/11 (55%)
		DUF3585	846..982	CDD:288945	8/36 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910