DRSC/TRiP Functional Genomics Resources

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Protein Alignment Pax and Synpo2l

DIOPT Version :9

Sequence 1:NP_001033913.1 Gene:Pax / 35215 FlyBaseID:FBgn0041789 Length:581 Species:Drosophila melanogaster
Sequence 2:NP_001297360.1 Gene:Synpo2l / 68760 MGIID:1916010 Length:978 Species:Mus musculus


Alignment Length:374 Identity:88/374 - (23%)
Similarity:127/374 - (33%) Gaps:114/374 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly     9 IDPGARQPYRTAR---SKGIL----PGYALLADLQNSVPGQPQQPQPQYGTVQPKHQALQQQQFV 66
            ||...||...|.|   .:|.:    ||     :||...|..|..|:|...   |..||||..   
Mouse    73 IDASGRQLVLTVRRVTDEGSVRSPSPG-----ELQVLSPLSPLSPEPPGA---PVSQALQPT--- 126

  Fly    67 DNTPGYGSLRGKAQPQVYQEHYSVETRSPTAGHDFNGSSTTPGYANQGSLPRQ------AAGAST 125
                   |||.....:.|   |. ||.|     |.:|.:|.       ..||:      |..:..
Mouse   127 -------SLRSPPDSEAY---YG-ETDS-----DVDGPATQ-------EKPRRTRRRGPARPSLP 168

  Fly   126 GLSELDSLLQDLQKIDVPVNYSTPVSKYNTMNSYATVE----ERPSVDSLLKELDNAHIYAVPNG 186
            |....:..|.|......||...:|....:.::|.:..|    :.|..::||          :|:|
Mouse   169 GAPPDEVYLSDSPAEPAPVKTGSPSQGDSRVSSPSWEEGAALQPPPAEALL----------LPHG 223

  Fly   187 SAHKSPTPGRHVTITVRETKTEKLTGPDGPV-GTVEEQIVQQKDSYTPNHAVPGQQVHQAYTSQA 250
            ...    ||.|:...|            ||| ..|.|.:.   .:||       |:..||...:|
Mouse   224 PLR----PGPHLIPMV------------GPVPHPVAEDLT---TTYT-------QKAKQAKLQRA 262

  Fly   251 TKELDDLMASLSDFKVSNGTNGIGNGSHPQQHSSTV-----QHQTVTDYARPNKGSQQAHLTQTI 310
             :.|.:  .|:.:.:....|......:.|..||..|     :.|....|...:.|:  |..|.|.
Mouse   263 -ESLQE--KSVKEARTKCRTIASLLTAAPNPHSKGVLMFKKRRQRAKKYTLVSFGA--AAGTGTE 322

  Fly   311 EETTIVEDSREDQLDS-------MLGN--------LQANMSRQGVNTVQ 344
            ||..|...| |.:||.       .|.|        |...::|.|:.|.:
Mouse   323 EEDGIPPTS-ESELDEETFSDARSLTNQSDWDSPYLDMELARAGLGTAE 370

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PaxNP_001033913.1 LIM1_Paxillin_like 348..400 CDD:259830
LIM2_Paxillin_like 407..458 CDD:188723
LIM3_Paxillin_like 466..518 CDD:188724
LIM4_Paxillin 525..576 CDD:188795
Synpo2lNP_001297360.1 PDZ_signaling 6..85 CDD:238492 5/11 (45%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 89..217 37/161 (23%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 317..352 11/35 (31%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 494..652
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 690..734
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 775..800
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1703
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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