DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pax and Isl1

DIOPT Version :9

Sequence 1:	NP_001033913.1	Gene:	Pax / 35215	FlyBaseID:	FBgn0041789	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	NP_059035.3	Gene:	Isl1 / 64444	RGDID:	61957	Length:	349	Species:	Rattus norvegicus

Alignment Length:	150	Identity:	45/150 - (30%)
Similarity:	63/150 - (42%)	Gaps:	21/150 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   407 CAYCNGAILDKCVTAL--DKTWHTEHFFCAQCGQQFGEE-GFHERDGKPYCRNDYFEMFAPKCNG 468
            |..|...|.|:.:..:  |..||.....||:|.|...|. ....||||.||:.||..::..||..
  Rat    17 CVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDGKTYCKRDYIRLYGIKCAK 81

  Fly   469 CNRAIMEN--YISALNSQWHPDCFVCRDC-RQPFQGGSFFDHEGLPYCET-HYHAKRGSLCAG-- 527
            |:....:|  .:.|.:..:|.:||.|..| ||...|..|...|...:|.. |...:|.||.||
  Rat    82 CSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALREDGLFCRADHDVVERASLGAGDP 146

  Fly   528 ------------CSKPITGR 535
                        .::||:.|
  Rat   147 LSPLHPARPLQMAAEPISAR 166

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pax	NP_001033913.1	LIM1_Paxillin_like	348..400	CDD:259830
		LIM2_Paxillin_like	407..458	CDD:188723	18/53 (34%)
		LIM3_Paxillin_like	466..518	CDD:188724	16/55 (29%)
		LIM4_Paxillin	525..576	CDD:188795	4/24 (17%)
Isl1	NP_059035.3	LIM1_Isl	17..71	CDD:188752	18/53 (34%)
		LIM2_Isl	79..133	CDD:188760	15/53 (28%)
		HOX	181..237	CDD:197696
		LIM-binding domain (LID). /evidence=ECO:0000250	262..291
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	312..349
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910