DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pax and Fhl5

DIOPT Version :9

Sequence 1:	NP_001033913.1	Gene:	Pax / 35215	FlyBaseID:	FBgn0041789	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	NP_001342427.1	Gene:	Fhl5 / 57756	MGIID:	1913192	Length:	284	Species:	Mus musculus

Alignment Length:	239	Identity:	67/239 - (28%)
Similarity:	101/239 - (42%)	Gaps:	14/239 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   348 CNACEKPIV--GQVITALGKTWHPEHFTCNHCSQELGTRNFFERDGFPYCEPDYHNLFSPRCAYC 410
            |..|::||.  .:.:....:.||...|.||.|...|..:.|..:|....|...|.|..|.:|.:|
Mouse    41 CEQCKEPIESDSKDLCYKNRHWHEGCFRCNKCHHSLVEKPFVAKDDRLLCTDCYSNECSSKCFHC 105

  Fly   411 NGAIL--DKCVTALDKTWHTEHFFCAQCGQQFGEEGFHERDGKPYCRNDYFEMFAPKCNGCNRAI 473
            ...|:  .:.:......||...|.|..|.|..|.:....::...||...:.:.||..||.|.:.|
Mouse   106 KRTIMPGSRKMEFKGNYWHETCFVCEHCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVI 170

  Fly   474 MENYISALNSQWHPDCFVCRDCRQPFQGGSFFDHEGLPY---CETHYHAKRGSLCAGCSKPITG- 534
            ....|:..:..||.:||:|..||:.....:|...:..|:   |..|.:||:   ||.|:|||||
Mouse   171 TSGGITFRDQIWHKECFLCSGCRKELYEEAFMSKDDFPFCLDCYNHLYAKK---CAACTKPITGL 232

  Fly   535 ---RCITAMFKKFHPEHFVCAFCLKQLNKGTFKEQKDKPYCHTC 575
               :.|....:::|.|.|.|..|...|....|.....:..|..|
Mouse   233 RGAKFICFQDRQWHSECFNCGKCSVSLVGEGFLTHNMEILCRKC 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pax	NP_001033913.1	LIM1_Paxillin_like	348..400	CDD:259830	14/53 (26%)
		LIM2_Paxillin_like	407..458	CDD:188723	12/52 (23%)
		LIM3_Paxillin_like	466..518	CDD:188724	16/54 (30%)
		LIM4_Paxillin	525..576	CDD:188795	18/55 (33%)
Fhl5	NP_001342427.1	LIM	<3..34	CDD:413332
		LIM1_FHL	37..95	CDD:188729	14/53 (26%)
		LIM2_FHL5	102..155	CDD:188812	12/52 (23%)
		LIM	163..214	CDD:413332	14/50 (28%)
		LIM4_FHL	222..277	CDD:188733	18/55 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000055
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910