DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pax and lhx4

DIOPT Version :9

Sequence 1:	NP_001033913.1	Gene:	Pax / 35215	FlyBaseID:	FBgn0041789	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	NP_001116445.1	Gene:	lhx4 / 571943	ZFINID:	ZDB-GENE-060728-1	Length:	391	Species:	Danio rerio

Alignment Length:	178	Identity:	56/178 - (31%)
Similarity:	77/178 - (43%)	Gaps:	29/178 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   405 PRCAYCNGAILDKCV-TALDKTWHTEHFFCAQCGQQFGEEGFHERDGKPYCRNDYFEMFAPKCNG 468
            |:||.|:..||||.: ..||:.||::...||.|.....::.| .|.|..||:.|:|:.|..||..
Zfish    31 PQCAGCSQHILDKFILKVLDRHWHSKCLKCADCHALLADKCF-SRAGNVYCKEDFFKRFGTKCAS 94

  Fly   469 CNRAIMENYI--SALNSQWHPDCFVCRDC-RQPFQGGSFF-DHEGLPYCETHYH-AKRGSLC-AG 527
            |.:.|....:  .|.:..:|..||.|..| ||...|..|: ..:|...|:..|. ||:.... .|
Zfish    95 CQQGIPPTQVVRKAQDFVYHLHCFACVMCSRQLATGDEFYLMEDGRLVCKEDYETAKQNDDSETG 159

  Fly   528 CSKPITGRCITAMFKKFHPEHFVCAFCLKQLN--KGTFKEQKDKPYCH 573
            ..:|.|  .|||                |||.  |..:| ...||..|
Zfish   160 AKRPRT--TITA----------------KQLETLKSAYK-NSPKPARH 188

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pax	NP_001033913.1	LIM1_Paxillin_like	348..400	CDD:259830
		LIM2_Paxillin_like	407..458	CDD:188723	19/51 (37%)
		LIM3_Paxillin_like	466..518	CDD:188724	15/55 (27%)
		LIM4_Paxillin	525..576	CDD:188795	14/52 (27%)
lhx4	NP_001116445.1	LIM1_Lhx4	33..84	CDD:188852	19/51 (37%)
		LIM2_Lhx3_Lhx4	92..147	CDD:188762	15/54 (28%)
		Homeobox	163..216	CDD:278475	13/45 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910