DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pax and lims1

DIOPT Version :9

Sequence 1:	NP_001033913.1	Gene:	Pax / 35215	FlyBaseID:	FBgn0041789	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	XP_021335295.1	Gene:	lims1 / 554019	ZFINID:	ZDB-GENE-050522-236	Length:	345	Species:	Danio rerio

Alignment Length:	240	Identity:	78/240 - (32%)
Similarity:	123/240 - (51%)	Gaps:	9/240 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   347 CCNACEKPIVGQVITALGKTWHPEHFTCNHCSQELGTRNFFERDGFPYCEPDYHNLFSPR----- 406
            ||:.|.:.|:|:||.|:..:|||:.|.|:.|...|....|.:..|...|.| .||....|
Zfish    81 CCHQCGEFIIGRVIKAMNNSWHPDCFCCDICQAVLADVGFVKNAGRHLCRP-CHNREKARGLGKY 144

  Fly   407 -CAYCNGAILDKCVTALDKTWHTEHFFCAQCGQQFGEEGFHERDGKPYCRNDYFEMFAPKCNGCN 470
             |..|:..|.::.:...:..:|.:||.|:.||::...:. .|..|:.||...:.:|..|.|..|.
Zfish   145 ICQKCHAIIEEQPLIFKNDPYHPDHFNCSNCGKELTADA-RELKGELYCLPCHDKMGVPICGACR 208

  Fly   471 RAIMENYISALNSQWHPDCFVCRDCRQPFQGGSFFDHEGLPYCETHYHAKRGSLCAGCSKPITGR 535
            |.|....::|:..|||.:.|||..|.:||.|...::.:||.||||||:...|.:|..|::.|.|.
Zfish   209 RPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGDVCYHCNRVIEGD 273

  Fly   536 CITAMFKKFHPEHFVCAFCLKQLN-KGTFKEQKDKPYCHTCFDKI 579
            .::|:.|.:....|.|:.|..:|. |..|.|...||.|..|::::
Zfish   274 VVSALNKAWCVNCFSCSTCNTKLTLKDRFVEVDLKPVCKHCYERL 318

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pax	NP_001033913.1	LIM1_Paxillin_like	348..400	CDD:259830	18/51 (35%)
		LIM2_Paxillin_like	407..458	CDD:188723	13/50 (26%)
		LIM3_Paxillin_like	466..518	CDD:188724	22/51 (43%)
		LIM4_Paxillin	525..576	CDD:188795	16/51 (31%)
lims1	XP_021335295.1	LIM1_PINCH	21..79	CDD:188717
		LIM2_PINCH	82..133	CDD:188718	18/51 (35%)
		LIM3_PINCH	146..196	CDD:188719	13/50 (26%)
		LIM4_PINCH	202..255	CDD:188720	22/52 (42%)
		LIM5_PINCH	263..316	CDD:188721	17/52 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1593918at2759
OrthoFinder	1	1.000	-	-		FOG0000055
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.920