DRSC/TRiP Functional Genomics Resources

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Protein Alignment Pax and Pdlim1

DIOPT Version :9

Sequence 1:NP_001033913.1 Gene:Pax / 35215 FlyBaseID:FBgn0041789 Length:581 Species:Drosophila melanogaster
Sequence 2:NP_058557.2 Gene:Pdlim1 / 54132 MGIID:1860611 Length:327 Species:Mus musculus


Alignment Length:298 Identity:64/298 - (21%)
Similarity:103/298 - (34%) Gaps:96/298 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   295 ARPNKGSQQAHLTQTIEETTIVEDSREDQLDSMLGNLQANMSRQGVNTVQKGCC-------NACE 352
            :|...||:.|.....|.:.....|..:   .|.:.:|:|.      |.: |||.       :..|
Mouse    31 SRVTPGSKAAIANLCIGDLITAIDGED---TSSMTHLEAQ------NKI-KGCADNMTLTVSRSE 85

  Fly   353 KPIVGQVITALGKTWHPEHFTCNHCSQ-----ELGTRNFFERDGFPY-CEP--------DYHNLF 403
            :.|...::|..||. ||  :..|..|:     .:|:.:  .|...|: ..|        :.:|  
Mouse    86 QKIWSPLVTEEGKR-HP--YKMNLASEPQEVLHIGSAH--NRSAMPFTASPAPSTRVITNQYN-- 143

  Fly   404 SPRCAYC-------NGAILDKCVTA-------------------LDKTWHTEHFFCAQCGQQFGE 442
            ||...|.       |.|:..|...:                   :||  .:|.:...|..|:..|
Mouse   144 SPTGLYSSENISNFNNAVESKTSASGEEANSRPVVQPHPSGSLIIDK--DSEVYKMLQEKQELNE 206

  Fly   443 -----------EGFHERDGK--PYCRNDYFEMFAPK---------------CNGCNRAIMENYIS 479
                       :...|.|||  |...:.:..:.||.               |:.|...|:..::.
Mouse   207 PPKQSTSFLVLQEILESDGKGDPNKPSGFRSVKAPVTKVAASVGNAQKLPICDKCGTGIVGVFVK 271

  Fly   480 ALNSQWHPDCFVCRDCRQPF-QGGSFFDHEGLPYCETH 516
            ..:...||:|:||.||.... |.|.||..:.: |||.|
Mouse   272 LRDHHRHPECYVCTDCGINLKQKGHFFVEDQI-YCEKH 308

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PaxNP_001033913.1 LIM1_Paxillin_like 348..400 CDD:259830 13/72 (18%)
LIM2_Paxillin_like 407..458 CDD:188723 15/89 (17%)
LIM3_Paxillin_like 466..518 CDD:188724 18/52 (35%)
LIM4_Paxillin 525..576 CDD:188795
Pdlim1NP_058557.2 PDZ_signaling 5..81 CDD:238492 13/59 (22%)
DUF4749 136..228 CDD:292558 17/95 (18%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 161..184 1/22 (5%)
LIM_CLP36 258..309 CDD:188832 18/52 (35%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1703
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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