DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pax and tes

DIOPT Version :9

Sequence 1:	NP_001033913.1	Gene:	Pax / 35215	FlyBaseID:	FBgn0041789	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	NP_001004961.1	Gene:	tes / 448383	XenbaseID:	XB-GENE-1015357	Length:	422	Species:	Xenopus tropicalis

Alignment Length:	314	Identity:	80/314 - (25%)
Similarity:	122/314 - (38%)	Gaps:	49/314 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   221 EEQIVQQKDSYTPNHAVPGQQVHQAYTSQATKELDDLMASLSDFKVSNGTNGIGNGSHPQQHSST 285
            ::|:.:|    .|.|.....:.|:...:: .|:::..:.     |..|...|:|:...|::
Frog   147 KKQLAKQ----LPAHDQDPSKCHELSPNE-VKQMEQFVK-----KYKNEVLGVGDVKLPKE---- 197

  Fly   286 VQHQTVTDYARPNKGSQQAHLTQTIEETTIVEDSREDQLDSMLGNLQANMSRQGVNTVQKGCCNA 350
            |:.| .....|...||... || |::.|   ||....|.:|..                  .|..
Frog   198 VEAQ-ACGAGRSTNGSLST-LT-TVKGT---EDKVAAQKESTY------------------YCFR 238

  Fly   351 CEK------PIVGQVITALGKTWHPEHFTCNHCSQELGTRNFFERDGFPYCEPDYHNLFSPRCAY 409
            |::      |.|........|.|||..|.|..|::.|....:|.::|..||...|.:...||||.
Frog   239 CKENMREGDPAVYAERAGYDKLWHPSCFVCFTCNELLVDMIYFWKNGKLYCGRHYCDSEKPRCAG 303

  Fly   410 CNGAILDKCVT-ALDKTWHTEHFFCAQCGQQFGEEGFHERDGKPYCRNDYFEMFAPKCNGCNRAI 473
            |:..|.....| |....||.:||.|..|......|.:...:.||.|:..|.:..|..|.||:.||
Frog   304 CDELIFSNEYTQAEGLNWHLKHFCCFDCDCVLAGEIYVMVNDKPVCKLCYVKNHAVSCQGCHNAI 368

  Fly   474 MENY--ISALNSQWH--PDCFVCRDCRQPFQGGSFFDHEGLPYCETHYHAKRGS 523
            ....  :|.....||  |:||:|..|.:...|..|...:|:.:|......|..|
Frog   369 DPEVQRVSYNGFHWHAAPECFICSCCSKCLIGQKFMPIQGMVFCSVDCKKKMSS 422

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pax	NP_001033913.1	LIM1_Paxillin_like	348..400	CDD:259830	16/57 (28%)
		LIM2_Paxillin_like	407..458	CDD:188723	16/51 (31%)
		LIM3_Paxillin_like	466..518	CDD:188724	17/55 (31%)
		LIM4_Paxillin	525..576	CDD:188795
tes	NP_001004961.1	PET_testin	109..195	CDD:193604	10/57 (18%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	135..165		4/21 (19%)
		LIM1_Testin	236..293	CDD:188797	16/56 (29%)
		LIM2_Testin	299..354	CDD:188800	18/54 (33%)
		LIM3_Testin	361..419	CDD:188803	17/57 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910