DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pax and fhl5

DIOPT Version :9

Sequence 1:	NP_001033913.1	Gene:	Pax / 35215	FlyBaseID:	FBgn0041789	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	NP_001004112.1	Gene:	fhl5 / 445475	ZFINID:	ZDB-GENE-040822-3	Length:	280	Species:	Danio rerio

Alignment Length:	280	Identity:	75/280 - (26%)
Similarity:	118/280 - (42%)	Gaps:	45/280 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   325 DSMLG-----------------NLQANMSRQGVNTVQKGCCNACEKPIVG---QVITALGKTWHP 369
            |::||                 ||.||            ||..|..|| |   :.::...:.||.
Zfish    13 DTLLGKKYILKEDTQYCTKCYENLFAN------------CCEVCSLPI-GCNCKDLSYKDRHWHE 64

  Fly   370 EHFTCNHCSQELGTRNFFERDGFPYCEPDYHNLFSPRCAYCNGAIL--DKCVTALDKTWHTEHFF 432
            ..|.|..||:.|..:.|..:|....|...|.:.:|.:|:.|...::  .:.:.....:||...|.
Zfish    65 NCFKCAKCSRSLVDKPFAAKDELMLCTECYSHEYSSKCSTCKKTVMPGSRKMEYKGNSWHETCFL 129

  Fly   433 CAQCGQQFGEEGFHERDGKPYCRNDYFEMFAPKCNGCNRAIMENYISALNSQWHPDCFVCRDCRQ 497
            |.:|.|..|.:.|..:|...:|...:.:.||.:|..|.:||....::..:..||.:||.|..|::
Zfish   130 CQRCQQPIGTKSFIPKDNNYFCVPCFEKQFAYQCCACKKAITTGGVTYHDKPWHRECFTCIGCKR 194

  Fly   498 PFQGGSFFDHEGLPY---CETHYHAKRGSLCAGCSKPIT----GRCITAMFKKFHPEHFVCAFCL 555
            ...|..|...|..||   |.::.:||:   |.||:|.||    .:.|:...:::|.|.|.|..|.
Zfish   195 QLAGQRFTSRENYPYCLDCFSNLYAKK---CVGCTKAITSLAGAKYISFEERQWHSECFTCMQCS 256

  Fly   556 KQLNKGTFKEQKDKPYCHTC 575
            ..|....|..|:|...|..|
Zfish   257 VSLVGRGFLTQRDDILCTDC 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pax	NP_001033913.1	LIM1_Paxillin_like	348..400	CDD:259830	15/54 (28%)
		LIM2_Paxillin_like	407..458	CDD:188723	12/52 (23%)
		LIM3_Paxillin_like	466..518	CDD:188724	16/54 (30%)
		LIM4_Paxillin	525..576	CDD:188795	18/55 (33%)
fhl5	NP_001004112.1	LIM	<6..34	CDD:295319	3/20 (15%)
		LIM1_FHL	37..95	CDD:188729	18/70 (26%)
		LIM	102..158	CDD:295319	12/55 (22%)
		LIM3_FHL	163..214	CDD:188732	15/50 (30%)
		LIM4_FHL	222..277	CDD:188733	18/55 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000055
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910