DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pax and LHX8

DIOPT Version :9

Sequence 1:	NP_001033913.1	Gene:	Pax / 35215	FlyBaseID:	FBgn0041789	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	XP_016856805.1	Gene:	LHX8 / 431707	HGNCID:	28838	Length:	363	Species:	Homo sapiens

Alignment Length:	116	Identity:	34/116 - (29%)
Similarity:	50/116 - (43%)	Gaps:	5/116 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   407 CAYCNGAILDKCVTAL-DKTWHTEHFFCAQCGQQFGEE-GFHERDGKPYCRNDYFEMFAPKCNGC 469
            |..|...|:||.:..: |..||.....|:.|....|.. ..:.:|...:|:.|||..:..:|:.|
Human    65 CNSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSLGRHTSCYIKDKDIFCKLDYFRRYGTRCSRC 129

  Fly   470 NRAI-MENYI-SALNSQWHPDCFVCRDC-RQPFQGGSFFDHEGLPYCETHY 517
            .|.| ..::: .|..:.:|..||.|..| ||...|..|...|....|..||
Human   130 GRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGEEFALVEEKVLCRVHY 180

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pax	NP_001033913.1	LIM1_Paxillin_like	348..400	CDD:259830
		LIM2_Paxillin_like	407..458	CDD:188723	13/52 (25%)
		LIM3_Paxillin_like	466..518	CDD:188724	18/55 (33%)
		LIM4_Paxillin	525..576	CDD:188795
LHX8	XP_016856805.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910