Protein Alignment Pax and LPP

DIOPT Version :9

• Sequence 1: NP_001033913.1
• Gene: Pax / 35215
• FlyBaseID: FBgn0041789
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: XP_011511125.1
• Gene: LPP / 4026
• HGNCID: 6679
• Length: 637
• Species: Homo sapiens
• Alignment Length: 593
• Identity: 125/593 - (21%)
• Similarity: 210/593 - (35%)
• Gaps: 192/593 - (32%)

  Fly    30 ALLADLQNSVPGQPQQPQPQYGTVQPKHQALQQQQFVDNTPGYGSLRGKAQPQVYQEHYSVETRS 94
            ::||||:.|.|.:|:.||...|:.                         |.|.|         .:
Human   151 SILADLECSSPYKPRPPQSSTGST-------------------------ASPPV---------ST 181

  Fly    95 PTAGHD------------FNGSSTTPGYANQ-GSLPRQAAGASTGLSELDSLLQDLQKIDVPVNY 146
            |..||.            ...|:..|..|.| |.:|         ::.:.:|....|  .||.:|
Human   182 PVTGHKRMVIPNQPPLTATKKSTLKPQPAPQAGPIP---------VAPIGTLKPQPQ--PVPASY 235

  Fly   147 STPVSKYNTMNSYATVEERPSVDSLLKELD-NAHIYAVP-NGSAHKSPTPGRHVTITVRETKTEK 209
            :|           |:...||:.:..:|... :.|..|.| :|..:.|...|.:       |:...
Human   236 TT-----------ASTSSRPTFNVQVKSAQPSPHYMAAPSSGQIYGSGPQGYN-------TQPVP 282

  Fly   210 LTGPDGPVGT--------VEEQIVQQKD--SYTPNHAVPGQQVHQAYTSQATKELDDLMASLSDF 264
            ::|...|..|        :....:|.:.  .|.||..    :.::.|                 :
Human   283 VSGQCPPPSTRGGMDYAYIPPPGLQPEPGYGYAPNQG----RYYEGY-----------------Y 326

  Fly   265 KVSNGTNGIGNGSHP----QQHSSTVQHQTVTDYARPNKGSQ------------QAHLTQTIE-- 311
            ....|..| .|.|.|    |.|.:|.:.:  ..|..|..|:|            :.::|..:.
Human   327 AAGPGYGG-RNDSDPTYGQQGHPNTWKRE--PGYTPPGAGNQNPPGMYPVTGPKKTYITDPVSAP 388

  Fly   312 ----------------ETTIVEDSR-EDQLDSMLGNLQANMSRQGVNTVQKGCCNACEKPIVGQ- 358
                            .:::....| ||:|:.:...:..:|.....:. ..|.|..|.:.:||:
Human   389 CAPPLQPKGGHSGQLGPSSVAPSFRPEDELEHLTKKMLYDMENPPADE-YFGRCARCGENVVGEG 452

  Fly   359 -VITALGKTWHPEHFTCNHCSQELGTRNFFERDGFPYCEPDYHNLFSPRCAYCNGAILDKCVTAL 422
             ..||:.:.:|.:.|||..|:.:|..:.|:..:...||||.|.|... :|..|:..|:::.:.|.
Human   453 TGCTAMDQVFHVDCFTCIICNNKLRGQPFYAVEKKAYCEPCYINTLE-QCNVCSKPIMERILRAT 516

  Fly   423 DKTWHTEHFFCAQCGQQFGEEGFHERDGKPY---------CRNDYFEMFAPKCNGCNRAIMEN-- 476
            .|.:|...|.|..|.:..        ||.|:         |..|:.:.|||:|:.|...||..
Human   517 GKAYHPHCFTCVMCHRSL--------DGIPFTVDAGGLIHCIEDFHKKFAPRCSVCKEPIMPAPG 573

  Fly   477 -----YISALNSQWHPDCFVCRDCRQPFQGG--SFFDHEGLPYCETHYHAKRGSLCAGCS----K 530
                 .|.||:..:|..|:.|.||     ||  |..|::|....:.|.      ||..|:    :
Human   574 QEETVRIVALDRDFHVHCYRCEDC-----GGLLSEGDNQGCYPLDGHI------LCKTCNSARIR 627

  Fly   531 PITGRCIT 538
            .:|.:..|
Human   628 VLTAKAST 635

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pax	NP_001033913.1	LIM1_Paxillin_like	348..400	CDD:259830	17/53 (32%)
		LIM2_Paxillin_like	407..458	CDD:188723	13/59 (22%)
		LIM3_Paxillin_like	466..518	CDD:188724	18/60 (30%)
		LIM4_Paxillin	525..576	CDD:188795	4/18 (22%)
LPP	XP_011511125.1	WWbp	<229..316	CDD:304964	21/106 (20%)
		LIM1_TRIP6	441..494	CDD:188736	17/52 (33%)
		LIM2_TRIP6	501..553	CDD:188742	13/59 (22%)
		LIM3_TRIP6	561..626	CDD:188820	21/75 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910