DRSC/TRiP Functional Genomics Resources

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Protein Alignment Pax and LIMS1

DIOPT Version :9

Sequence 1:NP_001033913.1 Gene:Pax / 35215 FlyBaseID:FBgn0041789 Length:581 Species:Drosophila melanogaster
Sequence 2:NP_001358423.1 Gene:LIMS1 / 3987 HGNCID:6616 Length:398 Species:Homo sapiens


Alignment Length:240 Identity:81/240 - (33%)
Similarity:124/240 - (51%) Gaps:9/240 - (3%)


- Green bases have known domain annotations that are detailed below.


  Fly   347 CCNACEKPIVGQVITALGKTWHPEHFTCNHCSQELGTRNFFERDGFPYCEPDYHNLFSPR----- 406
            ||:.|.:.|:|:||.|:..:||||.|.|:.|.:.|....|.:..|...|.| .||....|     
Human   132 CCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRP-CHNREKARGLGKY 195

  Fly   407 -CAYCNGAILDKCVTALDKTWHTEHFFCAQCGQQFGEEGFHERDGKPYCRNDYFEMFAPKCNGCN 470
             |..|:..|.::.:...:..:|.:||.||.||::...:. .|..|:.||...:.:|..|.|..|.
Human   196 ICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADA-RELKGELYCLPCHDKMGVPICGACR 259

  Fly   471 RAIMENYISALNSQWHPDCFVCRDCRQPFQGGSFFDHEGLPYCETHYHAKRGSLCAGCSKPITGR 535
            |.|....::|:..|||.:.|||..|.:||.|...::.:||.||||||:...|.:|..|::.|.|.
Human   260 RPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGDVCFHCNRVIEGD 324

  Fly   536 CITAMFKKFHPEHFVCAFCLKQLN-KGTFKEQKDKPYCHTCFDKI 579
            .::|:.|.:....|.|:.|..:|. |..|.|...||.|..|::|:
Human   325 VVSALNKAWCVNCFACSTCNTKLTLKDKFVEIDLKPVCKHCYEKM 369

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PaxNP_001033913.1 LIM1_Paxillin_like 348..400 CDD:259830 19/51 (37%)
LIM2_Paxillin_like 407..458 CDD:188723 14/50 (28%)
LIM3_Paxillin_like 466..518 CDD:188724 22/51 (43%)
LIM4_Paxillin 525..576 CDD:188795 16/51 (31%)
LIMS1NP_001358423.1 LIM1_PINCH 72..130 CDD:188717
LIM2_PINCH 133..184 CDD:188718 19/51 (37%)
LIM3_PINCH 197..247 CDD:188719 14/50 (28%)
LIM4_PINCH 253..306 CDD:188720 22/52 (42%)
LIM5_PINCH 314..367 CDD:188721 17/52 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1593918at2759
OrthoFinder 1 1.000 - - FOG0000055
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X39
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
43.920

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