DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pax and Ablim3

DIOPT Version :9

Sequence 1:	NP_001033913.1	Gene:	Pax / 35215	FlyBaseID:	FBgn0041789	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	NP_001157963.1	Gene:	Ablim3 / 319713	MGIID:	2442582	Length:	682	Species:	Mus musculus

Alignment Length:	251	Identity:	72/251 - (28%)
Similarity:	108/251 - (43%)	Gaps:	33/251 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   337 RQGVNTVQKGCCNACEKPIVGQVITALGKTWHPEHFTCNHCSQELGTRNFFERDGFPYCEPDYHN 401
            |.|.|.:|   |..|.....|:|:......:|...|||..|...|....||.::....|..||..
Mouse    15 RGGSNVIQ---CYRCGDTCKGEVVRVHNNHFHIRCFTCQVCGCGLAQSGFFFKNQEYICTQDYQQ 76

  Fly   402 LFSPRCAYCNGAILDKCVTALDKTWHTEHFFCAQCGQQF---------GEEGFHERDGKPYCRND 457
            |:..||..|...|..:.::||.:|:|.:.|.|:.|.:.|         |:|...:...:....:.
Mouse    77 LYGTRCDSCRDFITGEVISALGRTYHPKCFVCSLCRKPFPIGDKVTFSGKECVCQTCSQSMTSSK 141

  Fly   458 YFEMFAPK-CNGCNRAIMENY-ISALNSQWHPDCFVCRDCRQPFQGGSFFDHEGLPYCETHYHAK 520
            ..::..|. |.||...|.... :.||:.|||..||.|:.| .....|.:...:|:||||:.||::
Mouse   142 PIKIRGPSHCAGCKEEIKHGQSLLALDKQWHVSCFKCQTC-SVILTGEYISKDGVPYCESDYHSQ 205

  Fly   521 RGSLCAGCSKPITGRCITAMFKKFHPEHFVCAFCLKQLNKGTFKEQKDKPYCHTCF 576
            .|..|..|.:.|:||.:.|..|.:||   .||.|::               ||..|
Mouse   206 FGIKCETCDRYISGRVLEAGGKHYHP---TCARCVR---------------CHQMF 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pax	NP_001033913.1	LIM1_Paxillin_like	348..400	CDD:259830	14/51 (27%)
		LIM2_Paxillin_like	407..458	CDD:188723	13/59 (22%)
		LIM3_Paxillin_like	466..518	CDD:188724	19/52 (37%)
		LIM4_Paxillin	525..576	CDD:188795	14/50 (28%)
Ablim3	NP_001157963.1	LIM1_abLIM	23..74	CDD:188713	13/50 (26%)
		LIM2_abLIM	79..134	CDD:188714	14/54 (26%)
		LIM3_abLIM	151..202	CDD:188715	19/51 (37%)
		LIM4_abLIM	210..265	CDD:188716	15/52 (29%)
		AbLIM_anchor	273..645	CDD:374416
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	372..426
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	440..475
		VHP	647..682	CDD:128458
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910