DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pax and Mical1

DIOPT Version :9

Sequence 1:	NP_001033913.1	Gene:	Pax / 35215	FlyBaseID:	FBgn0041789	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	XP_038954550.1	Gene:	Mical1 / 294520	RGDID:	1309386	Length:	1058	Species:	Rattus norvegicus

Alignment Length:	289	Identity:	57/289 - (19%)
Similarity:	84/289 - (29%)	Gaps:	101/289 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 KIDPGARQP---------------YRTARSK-GILPG---------------YALLADLQNSVPG 41
            ::.||..:|               .|.|..: ||:|.               .|.|:...::...
  Rat   548 RLQPGLLEPSELQGMSALEATAWALRVAEYELGIIPVLSAQAVVAGSDPLGLIAYLSHFHSAFKN 612

  Fly    42 QPQQPQPQYGTVQPKHQALQQQQFVDNTPGYGSLRGKAQPQVYQEHYSVETRSP-TAGHDFNGSS 105
            .|...    |.|...|          .||......||.|..:.:....||..:| |.....:..|
  Rat   613 TPHSS----GLVSQPH----------GTPSAILFLGKLQRSLQRTRTKVEEETPCTEEPPVSEPS 663

  Fly   106 TTPGYANQGSLPRQAAGASTGLSELDSLLQDLQKIDV--------------------PVNYSTPV 150
            ..|...::    .:.|||..........|..|::..|                    |..|
  Rat   664 VPPALPSE----HEEAGAEDVCELCGKRLYILERFCVDGHFFHRGCFCCRTCEATLRPGGY---- 720

  Fly   151 SKYNTMNSYATVEERPSVDSLLKELDNAHIYAVPNGSAHKS--PTPGRHVTITVRETKTEKLTGP 213
            .:|.....:..::..|..|.  ||.||       |||....  ||||...|          .:||
  Rat   721 GQYPGDGYFYCLQHLPQEDQ--KEADN-------NGSPENQELPTPGDSTT----------QSGP 766

  Fly   214 DGPVGTVEEQIVQQKDSYTPNHAVPGQQV 242
            ..||..|.|.      |..|:.:.|.:::
  Rat   767 SSPVPPVTEA------SPVPSPSQPARRL 789

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pax	NP_001033913.1	LIM1_Paxillin_like	348..400	CDD:259830
		LIM2_Paxillin_like	407..458	CDD:188723
		LIM3_Paxillin_like	466..518	CDD:188724
		LIM4_Paxillin	525..576	CDD:188795
Mical1	XP_038954550.1	FAD_binding_3	85..>122	CDD:396193
		CH_MICAL1	506..611	CDD:409045	10/62 (16%)
		LIM	681..734	CDD:413332	6/56 (11%)
		DUF3585	929..1056	CDD:403377
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910