DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pax and rga1

DIOPT Version :9

Sequence 1:	NP_001033913.1	Gene:	Pax / 35215	FlyBaseID:	FBgn0041789	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	NP_596743.1	Gene:	rga1 / 2541022	PomBaseID:	SPBC3F6.05	Length:	1150	Species:	Schizosaccharomyces pombe

Alignment Length:	311	Identity:	82/311 - (26%)
Similarity:	130/311 - (41%)	Gaps:	74/311 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   191 SPTPGRHVTITVRETKTEKLTGPDGPVGTVEEQIVQQKDSYTPNHAVPGQQVHQAYTSQATKELD 255
            ||||.:.:.:..|:.|.|                   ::|.|.|..      |..:||...
pombe    19 SPTPPKRIPVPSRQNKIE-------------------ENSTTKNFP------HSRHTSTVA---- 54

  Fly   256 DLMASLSDFKVSNGTNGIGNGSHPQQHSSTVQHQTVTDYARPNKGSQQAHLTQTIEETTIVEDSR 320
                         ||.  |..|..::|:|....:     |.||:        |.:.::.::  ::
pombe    55 -------------GTE--GGSSLSRRHTSAESRK-----ALPNQ--------QQLAQSGLL--NK 89

  Fly   321 EDQLDSMLGNLQANMSRQGVNTVQKG-CCNACEKPIVGQVITALGKTWHPEHFTCNHCSQELGTR 384
            |:|  ..|.....::..:.|..|... .|.:|.:.|.||.:.|||..:|.|.|.|:.|:..:.::
pombe    90 EEQ--QSLKRSDTSVFPKAVRKVSSSKICASCGQVISGQYVRALGNIYHLECFRCHDCNSLVASK 152

  Fly   385 NFFERDG------FPYCEPDYHNLFSPRCAYCNGAILDKCVTALDKTWHTEHFFCAQCGQQFG-E 442
             ||..|.      .|.||.||.......||.|..|:....:|||:|.:|.|||.|:.|...|| .
pombe   153 -FFPIDDPTLNKQVPLCETDYFRRLDLLCASCGMALRGYYITALNKKFHIEHFTCSLCYTVFGPN 216

  Fly   443 EGFHERDGKPYCRNDYFEMFAPKCNGCN----RAIMENYISALNSQWHPDC 489
            :.::|.:||.||...|..:||.:|.||:    |..:|.|.:.::..||..|
pombe   217 DSYYEYEGKVYCHYHYSTLFAARCCGCDGPILRQFVEVYRNGVSQNWHVPC 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pax	NP_001033913.1	LIM1_Paxillin_like	348..400	CDD:259830	20/57 (35%)
		LIM2_Paxillin_like	407..458	CDD:188723	21/51 (41%)
		LIM3_Paxillin_like	466..518	CDD:188724	9/28 (32%)
		LIM4_Paxillin	525..576	CDD:188795
rga1	NP_596743.1	LIM1_Lrg1p_like	116..172	CDD:188777	19/56 (34%)
		LIM2_Lrg1p_like	180..232	CDD:188778	21/51 (41%)
		LIM	485..539	CDD:295319
		RhoGAP_fLRG1	835..1044	CDD:239862
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	49	1.000	Domainoid score	I3455
eggNOG	1	0.900	-	-		E1_KOG1703
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000055
OrthoInspector	1	1.000	-	-		otm47179
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1093
SonicParanoid	1	1.000	-	-		X39
TreeFam	0	0.000	Not matched by this tool.
	6	5.930