DRSC/TRiP Functional Genomics Resources

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Protein Alignment Pax and Pdlim4

DIOPT Version :9

Sequence 1:NP_001033913.1 Gene:Pax / 35215 FlyBaseID:FBgn0041789 Length:581 Species:Drosophila melanogaster
Sequence 2:NP_001380800.1 Gene:Pdlim4 / 24915 RGDID:3575 Length:335 Species:Rattus norvegicus


Alignment Length:368 Identity:74/368 - (20%)
Similarity:113/368 - (30%) Gaps:121/368 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly    88 YSVETRSPT-------AGHDFNGSSTTPGYANQGSLPRQAAGASTGLSELDSLLQDLQKIDVPVN 145
            :||..|.|:       .|.||:...|         :.|..||:...|:.|               
  Rat     3 HSVTLRGPSPWGFRLVGGRDFSAPLT---------ISRVHAGSKAALAAL--------------- 43

  Fly   146 YSTPVSKYNTMNSYATVEERPSVDSLLKELDNAHIYAVPNGSAHKSPTPGRHVTITVRETKTEKL 210
              .|......:|..:|            || ..|:.|       ::...|.|..:|:..::.|..
  Rat    44 --CPGDLIQAINGEST------------EL-MTHLEA-------QNRIKGCHDHLTLSVSRPENK 86

  Fly   211 TGPDGPVGTVEEQIVQQKDSYTPNHAVPGQQVHQAYTSQATKELDDLMASLSDFKVSNGTNGIG- 274
            ..|..|            |.....|.:......||...|.........:|:|...:.:..:|:| 
  Rat    87 NWPSSP------------DDKAQAHRIHIDPEAQASLLQDGSPATSRRSSISGISLEDNRSGLGS 139

  Fly   275 ------------NGSH-----PQQHSSTVQHQTVTDYA------------RPNKGSQQAHLTQTI 310
                        |||.     |.|.|:.  |.:....|            |.:.||:...:.:..
  Rat   140 PYGQPPRLPVPHNGSSNEVTLPSQMSAL--HVSPPPSADTPRILPRNRDCRVDLGSEVYRMLREP 202

  Fly   311 EETTIVEDSREDQLDSMLGNLQANM---------SR-------------QGVNTVQKGCCNACEK 353
            .|....|..:......:.|.|:|..         ||             .|:..:.:  |..|..
  Rat   203 AEPAASEPKQSGSFRYLQGMLEAGEGGDRPGSGGSRNLKPAASKLGAPLSGLQGLPE--CTRCGH 265

  Fly   354 PIVGQVITALGKTWHPEHFTCNHCSQELGTRNFFERDGFPYCE 396
            .|||.::.|..|.:|||.|.|:.|...|..|.:|..|...|||
  Rat   266 GIVGTIVKARDKLYHPECFMCSDCGLNLKQRGYFFLDERLYCE 308

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PaxNP_001033913.1 LIM1_Paxillin_like 348..400 CDD:259830 20/49 (41%)
LIM2_Paxillin_like 407..458 CDD:188723
LIM3_Paxillin_like 466..518 CDD:188724
LIM4_Paxillin 525..576 CDD:188795
Pdlim4NP_001380800.1 PDZ_signaling 2..80 CDD:238492 23/122 (19%)
DUF4749 139..235 CDD:406377 16/97 (16%)
LIM_RIL 260..312 CDD:188835 20/49 (41%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1703
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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